Description
Specifications Table
| Product Name | 17-AAG (17-Allylamino-17-Demethoxygeldanamycin) |
|---|---|
| Quantity/Pack Size | 1 mg |
| Form | Powder |
| Grade | Research Grade |
| Application | HSP90 inhibitor for research purposes |
Product Description
17-AAG, also known as 17-Allylamino-17-Demethoxygeldanamycin, is a highly effective HSP90 inhibitor widely used in research settings. This compound is particularly noted for its anticancer properties, making it a valuable tool for scientists and researchers studying cancer biology and potential therapeutic interventions. At eqipped, we offer 17-AAG in a convenient 1 mg pack size, ensuring you have the right quantity for your experiments.
17-AAG is a derivative of geldanamycin, a natural product isolated from Streptomyces hygroscopicus. The allylamino group at the 17-position enhances its solubility and stability, making it a more practical choice for in vitro and in vivo studies. Its ability to inhibit HSP90, a molecular chaperone crucial for the proper folding and stabilization of numerous client proteins, has made it a focal point in cancer research.
Researchers often use 17-AAG to study the mechanisms of protein degradation and the role of HSP90 in various cellular processes. By inhibiting HSP90, 17-AAG can lead to the degradation of oncogenic proteins, thereby disrupting cancer cell survival and proliferation. This makes it an invaluable tool for understanding the molecular pathways involved in cancer and for developing new therapeutic strategies.
Buy 17-AAG for your research needs today!
At eqipped, we understand the importance of high-quality lab supplies for accurate and reliable research outcomes. Our 17-AAG is sourced from reputable manufacturers and undergoes rigorous quality control to ensure it meets the highest standards. Whether you are a student, researcher, or educator, you can trust eqipped to provide you with the best products for your scientific endeavors.
17-AAG is not just a chemical; it’s a key to unlocking new insights in cancer research. Its unique properties make it an essential component in the toolkit of any researcher studying HSP90 and its role in cancer biology. By using 17-AAG, you can contribute to the development of new therapies that could one day improve the lives of cancer patients.
Ready to advance your research with 17-AAG? Shop now at eqipped!
FAQs
What is 17-AAG used for in research?
17-AAG is primarily used as an HSP90 inhibitor in cancer research. It helps in studying the mechanisms of protein degradation and the role of HSP90 in various cellular processes.
Is 17-AAG safe to handle?
17-AAG should be handled with care as it is a high-risk chemical. Always use appropriate personal protective equipment (PPE) and follow safety guidelines when handling this compound.
What is the recommended storage condition for 17-AAG?
17-AAG should be stored at -20°C in a dry, well-ventilated area away from heat sources and incompatible substances.
Can 17-AAG be used in vivo studies?
Yes, 17-AAG can be used in both in vitro and in vivo studies. Its enhanced solubility and stability make it suitable for various research applications.
How does 17-AAG inhibit HSP90?
17-AAG binds to the ATP-binding pocket of HSP90, preventing it from interacting with its client proteins. This leads to the degradation of the client proteins, disrupting cellular processes and ultimately leading to cell death in cancer cells.
