Description
Specifications Table
| Product Name | Fmoc-Gln(Trt)-Wang Resin (100-200 Mesh) | 8.56007.0100 | Merck |
|---|---|
| Pack Size | 100 G |
| Form | Resin beads |
| Grade | High-purity, peptide synthesis grade |
| Application | Solid-phase peptide synthesis (SPPS), Fmoc chemistry |
Product Description
When precision matters in peptide synthesis, Fmoc-Gln(Trt)-Wang Resin from Merck delivers consistent performance. This high-purity resin, pre-loaded with Fmoc-Gln(Trt), is designed for solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The 100-200 mesh size ensures optimal swelling and reactivity, making it a trusted choice for researchers and labs across India.
Whether you’re synthesizing complex peptides or optimizing yields, this resin offers excellent loading capacity and stability. The Trt (trityl) protecting group on glutamine ensures minimal side reactions, while the Wang linker allows for clean cleavage under mild acidic conditions. Ideal for both academic and industrial applications, this resin is a staple in modern peptide chemistry.
At eqipped, we understand the importance of reliable lab supplies. That’s why we source directly from Merck to guarantee authenticity and performance. Shop now for fast, pan-India delivery and competitive pricing on premium peptide synthesis resins.
Why This Resin Stands Out
Not all peptide synthesis resins are created equal. Here’s what sets this product apart:
The 100-200 mesh size balances surface area and mechanical stability, reducing clogging in automated synthesizers. The Fmoc-Gln(Trt) pre-loading saves time and eliminates the need for manual coupling, while the Wang linker ensures high-purity cleavage with TFA. Researchers appreciate its low non-specific binding, which minimizes impurities in final peptides.
For labs scaling up production, this resin’s batch-to-batch consistency is a game-changer. Merck’s rigorous quality control means you get the same performance every time—critical for reproducible results in drug discovery, vaccine development, or biochemical studies.
Applications in Research and Industry
This resin is versatile enough for a range of applications:
In academic labs, it’s used for synthesizing custom peptides for structural biology or enzyme studies. Pharmaceutical R&D teams rely on it for therapeutic peptide development, including antimicrobial peptides and hormone analogs. Even educational institutions use it to teach students the fundamentals of SPPS.
Industries like biotech and contract research organizations (CROs) prefer this resin for its scalability—whether you’re producing milligrams for screening or grams for preclinical trials. The Trt protection is particularly valuable when working with glutamine-rich sequences, preventing glutarimide formation during synthesis.
Handling and Storage Tips
To maintain performance, store the resin in a cool, dry place away from moisture. Always use anhydrous solvents like DMF or DCM for swelling and washing. If you notice discoloration or clumping, it may indicate degradation—discard and use a fresh batch.
For long-term storage, keep the resin in its original packaging with desiccants. Once opened, reseal tightly to prevent humidity exposure. Pro tip: Equilibrate the resin in your synthesis solvent for 30 minutes before use to ensure uniform swelling.
Safety and Compliance
While this resin is generally safe for lab use, follow standard precautions:
- Wear nitrile gloves and safety goggles when handling.
- Avoid inhaling resin dust—work in a fume hood if processing large quantities.
- Dispose of waste resin according to your institution’s chemical waste guidelines.
This product complies with Merck’s quality standards and is suitable for research use only. Not intended for human or veterinary applications.
Ready to Elevate Your Peptide Synthesis?
With Fmoc-Gln(Trt)-Wang Resin from Merck, you’re choosing a product trusted by researchers worldwide. Order today at eqipped and experience seamless peptide synthesis with guaranteed quality and fast shipping.
FAQs
1. What is the loading capacity of this Fmoc-Gln(Trt)-Wang Resin?
The typical loading capacity ranges from 0.5 to 0.8 mmol/g, depending on the batch. Check the certificate of analysis (CoA) for exact values.
2. Can I use this resin for C-terminal amide peptides?
Yes, the Wang linker is ideal for generating C-terminal amides upon cleavage with TFA. It’s a popular choice for peptides requiring this modification.
3. How do I calculate the amount of resin needed for my synthesis?
Use this formula: Resin weight (g) = (Desired peptide mmol) / (Resin loading mmol/g) × 1.2 (to account for excess). For example, for 0.1 mmol of peptide with 0.6 mmol/g loading: 0.1 / 0.6 × 1.2 = 0.2 g.
4. What solvents are compatible with this resin?
Common solvents include DMF, DCM, NMP, and DMSO. Avoid prolonged exposure to strong acids or bases, which may degrade the linker or protecting groups.
5. Does eqipped provide bulk discounts for this resin?
Yes, we offer competitive pricing for bulk orders. Contact our sales team at [support@eqipped.in] for quotes on larger quantities.
