Description
Specifications Table
| Product Name | Fmoc-His(Trt)-Wang Resin (100-200 Mesh) | 8.56010.0005 | Merck |
|---|---|
| Pack Size | 5 G |
| Form | Resin |
| Grade | For Synthesis |
| Application | Peptide Synthesis |
Product Description
Fmoc-His(Trt)-Wang Resin is a high-performance solid-phase synthesis resin designed for efficient peptide assembly. With a mesh size of 100-200, this resin ensures optimal swelling properties and coupling efficiency, making it a preferred choice for researchers and labs working on peptide-based projects. The Fmoc-protected histidine with trityl (Trt) side-chain protection allows for clean deprotection and high-purity synthesis.
This resin is particularly useful in the synthesis of histidine-containing peptides, where precise control over side-chain protection is critical. The Wang linker provides stability during synthesis while enabling mild cleavage conditions, ensuring the integrity of the final peptide product.
Whether you’re working on therapeutic peptides, biochemical studies, or academic research, this resin delivers consistent results. eqipped offers this Merck product in a convenient 5g pack, ensuring you have the right quantity for your lab needs without excess waste.
Upgrade your peptide synthesis workflow with high-quality Fmoc-His(Trt)-Wang Resin. Order now for reliable performance in every batch.
Why This Resin Stands Out
The 100-200 mesh size strikes the perfect balance between surface area and mechanical stability, reducing the risk of bead fragmentation during synthesis. The Trt protection on histidine prevents side reactions, while the Fmoc group allows for standard deprotection protocols. This combination makes it one of the most reliable resins for histidine incorporation in peptides.
Researchers in India trust this resin for its reproducibility and compatibility with automated synthesizers. Whether you’re synthesizing short peptides or complex sequences, this resin maintains its performance across multiple cycles.
Applications in Research
This resin is widely used in:
- Therapeutic peptide development
- Protein-protein interaction studies
- Enzyme substrate synthesis
- Academic research in biochemistry
Its versatility makes it a staple in labs focusing on drug discovery, structural biology, and synthetic biology.
Handling and Storage
Store the resin in a cool, dry place away from moisture. For best results, use within the recommended shelf life and avoid prolonged exposure to air. Always follow standard lab safety protocols when handling chemical resins.
FAQs
What is the loading capacity of this Fmoc-His(Trt)-Wang Resin?
The typical loading capacity ranges between 0.5-1.0 mmol/g, depending on the batch. For precise values, refer to the certificate of analysis provided with your order.
Can this resin be used in automated peptide synthesizers?
Yes, this resin is compatible with most automated synthesizers. Its uniform bead size ensures smooth flow through synthesis columns.
What cleavage conditions are recommended for this resin?
Standard TFA-based cleavage cocktails work well. A typical mixture includes 95% TFA, 2.5% water, and 2.5% triisopropylsilane for optimal results.
Is this resin suitable for C-terminal peptide amides?
Yes, the Wang linker allows for the synthesis of C-terminal peptide amides when using appropriate cleavage conditions.
How should I store unused resin?
Keep the resin in its original packaging or an airtight container at 2-8°C. Avoid freeze-thaw cycles to maintain its performance.
