Description
Specifications Table
| Product Name | Fmoc-Lys(Mtt)-Wang Resin Ll 100 G |
|---|---|
| Pack Size | 100 G |
| Form | Resin |
| Grade | Research Grade |
| Application | Peptide Synthesis |
Product Description
When it comes to peptide synthesis, the quality of your resin can make or break your results. Fmoc-Lys(Mtt)-Wang Resin is a specialized solid-phase synthesis resin designed for researchers and students who demand precision. This resin features the Mtt (4-methyltrityl) protecting group, which allows for selective deprotection of lysine during synthesis, making it a versatile choice for complex peptide sequences.
Whether you’re working on academic research or small-scale peptide production, this resin ensures high coupling efficiency and minimal side reactions. The Wang resin backbone provides excellent swelling properties in common solvents like DMF and DCM, making it compatible with standard Fmoc chemistry protocols.
At eqipped, we understand the importance of reliable lab supplies. That’s why we source this resin directly from Merck, ensuring you receive a product that meets rigorous quality standards. If you’re looking to buy Fmoc-Lys(Mtt)-Wang Resin online, you’ll find competitive pricing and fast shipping across India.
Upgrade your peptide synthesis workflow with high-purity Fmoc-Lys(Mtt)-Wang Resin. Order today and experience the difference in your research outcomes.
Why This Resin Stands Out
Peptide synthesis requires resins that balance reactivity with stability. This particular resin offers several advantages:
First, the Mtt protecting group is orthogonal to Fmoc chemistry, allowing for selective deprotection without affecting other amino acids. This is particularly useful when synthesizing peptides with multiple lysine residues or when you need to introduce modifications like biotinylation or fluorescence labeling.
Second, the Wang resin linker is acid-labile, which means your final peptide can be cleaved under mild conditions using TFA. This reduces the risk of side reactions that can occur with harsher cleavage methods.
Finally, the resin’s uniform bead size ensures consistent loading and efficient solvent penetration, which translates to higher yields and purer peptides. For researchers working on demanding projects, these small details can significantly impact your results.
Applications in Research
This resin is widely used in both academic and industrial settings for:
Synthesizing peptides with post-translational modifications, such as phosphorylated or glycosylated peptides. The selective deprotection of Mtt allows for precise control over where modifications are introduced.
Creating branched peptides or peptide dendrimers, where lysine residues serve as branching points. The Mtt group can be removed to expose the epsilon-amino group for further conjugation.
Developing peptide-based therapeutics or diagnostic tools. The high purity and consistency of this resin make it suitable for applications where reproducibility is critical.
If you’re a student learning peptide synthesis techniques, this resin provides a reliable foundation for your experiments. Its predictable behavior makes it easier to troubleshoot and optimize your protocols.
Handling and Storage
To maintain the integrity of your Fmoc-Lys(Mtt)-Wang Resin, store it in a cool, dry place away from direct sunlight. The resin should be kept in its original packaging or an airtight container to prevent moisture absorption, which can affect its performance.
Before use, allow the resin to equilibrate to room temperature to avoid condensation. If you’re working in a humid environment, consider using a desiccant in your storage container.
Need a reliable supplier for your peptide synthesis needs? Buy Fmoc-Lys(Mtt)-Wang Resin online from eqipped and get authentic Merck products delivered to your lab.
Safety Considerations
While this resin is generally safe to handle, it’s important to follow standard laboratory practices. Wear appropriate personal protective equipment, including gloves and safety goggles, when handling the resin. Avoid inhaling dust or particles, and work in a well-ventilated area or fume hood.
In case of skin or eye contact, rinse thoroughly with water and seek medical advice if irritation persists. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.
FAQs
What is the loading capacity of Fmoc-Lys(Mtt)-Wang Resin?
The typical loading capacity ranges from 0.5 to 0.8 mmol/g, depending on the batch. For precise values, refer to the certificate of analysis provided with your order.
Can this resin be used for continuous flow peptide synthesis?
Yes, this resin is compatible with both batch and continuous flow synthesis methods. Its uniform bead size makes it suitable for flow chemistry applications.
How do I deprotect the Mtt group?
The Mtt group can be selectively removed using a mild acid solution, such as 1% TFA in DCM. This allows for orthogonal deprotection without affecting Fmoc groups.
What is the shelf life of this resin?
When stored properly in a cool, dry place, the resin has a shelf life of at least 12 months. Always check the expiration date on the packaging before use.
Does eqipped offer bulk discounts on this product?
Yes, we provide competitive pricing for bulk orders. Contact our sales team for a customized quote based on your requirements.
