Description
Specifications Table
| Product Name | Fmoc-Thr(Po(Obzl)Oh)-Oh |
|---|---|
| Pack Size | 5 G |
| Form | Solid |
| Grade | Peptide Synthesis Grade |
| Application | Solid-Phase Peptide Synthesis (SPPS) |
Product Description
What is Fmoc-Thr(Po(Obzl)Oh)-Oh?
Fmoc-Thr(Po(Obzl)Oh)-Oh is a protected threonine derivative widely used in peptide synthesis. The Fmoc (9-fluorenylmethoxycarbonyl) group protects the amino terminus, while the benzyl-protected phosphate group ensures stability during synthesis. This compound is essential for researchers and chemists working on solid-phase peptide synthesis (SPPS), enabling precise control over peptide sequences.
Key Applications in Research
This reagent is a staple in biochemical and pharmaceutical laboratories. It is commonly used in the synthesis of phosphopeptides, which are critical for studying protein phosphorylation pathways. Researchers rely on Fmoc-Thr(Po(Obzl)Oh)-Oh to create modified peptides for drug discovery, enzyme studies, and structural biology. Its high purity ensures minimal side reactions, making it ideal for sensitive applications.
Why This Grade Matters
The peptide synthesis grade of this product guarantees consistency and reliability in experimental results. Unlike lower-grade alternatives, this version undergoes rigorous purification to remove impurities that could interfere with synthesis. Whether you’re working on academic research or industrial applications, using a high-quality reagent like this one ensures reproducibility and accuracy.
How to Use Fmoc-Thr(Po(Obzl)Oh)-Oh
For optimal results, follow standard SPPS protocols. Dissolve the reagent in an appropriate solvent (e.g., DMF or DCM) and couple it to the growing peptide chain using standard coupling reagents like HATU or DIC. The Fmoc group can be easily removed with piperidine, allowing for further chain elongation. Always store the product in a dry, inert atmosphere to prevent degradation.
Storage and Handling
Store this product at -20°C in a desiccator to maintain stability. Avoid exposure to moisture, as it can lead to hydrolysis of the phosphate group. When handling, use appropriate personal protective equipment (PPE), including gloves and safety goggles, to minimize risk.
Where to Buy Fmoc-Thr(Po(Obzl)Oh)-Oh Online
Finding a reliable supplier for high-quality peptide synthesis reagents can be challenging. At eqipped, we ensure that every batch of Fmoc-Thr(Po(Obzl)Oh)-Oh meets strict quality standards. Our platform offers a seamless purchasing experience, with fast shipping and dedicated customer support to assist with any queries.
Looking for bulk quantities or custom packaging? Contact our team for tailored solutions.
FAQs
What is the shelf life of Fmoc-Thr(Po(Obzl)Oh)-Oh?
When stored properly at -20°C, this product has a shelf life of at least 12 months. Always check the certificate of analysis for specific batch details.
Can this reagent be used for solution-phase peptide synthesis?
While primarily designed for SPPS, it can be adapted for solution-phase synthesis with appropriate modifications to the deprotection and coupling steps.
What solvents are compatible with this compound?
Common solvents include DMF, DCM, and DMSO. Avoid protic solvents like water or alcohols, as they may cause premature deprotection.
Is this product suitable for automated peptide synthesizers?
Yes, it is compatible with most automated SPPS systems. Ensure proper solvent and reagent compatibility with your specific instrument.
How does eqipped ensure the quality of this product?
We source directly from Merck and conduct additional quality checks to verify purity and consistency. Each batch comes with a certificate of analysis for transparency.
