Description
Specifications Table
| Product Name | H-Arg(Pbf)-2-Cltrt Resin 5 G | 8.56067.0005 | Merck |
|---|---|
| Quantity/Pack Size | 5 G |
| Form | Resin |
| Grade | Laboratory Grade |
| Application | Solid-Phase Peptide Synthesis (SPPS) |
Product Description
When it comes to peptide synthesis, the quality of your resin can make or break your research. H-Arg(Pbf)-2-Cltrt Resin from Merck is a premium FMOC-protected resin designed specifically for solid-phase peptide synthesis (SPPS). Whether you’re a student working on a thesis or a researcher developing novel peptides, this resin ensures high coupling efficiency and minimal side reactions.
This lab-grade resin is pre-loaded with the arginine derivative H-Arg(Pbf), which is protected with the Pbf group to prevent unwanted reactions during synthesis. The 2-chlorotrityl (2-Cltrt) linker allows for mild cleavage conditions, making it ideal for sensitive peptide sequences. With a pack size of 5 grams, it’s perfect for small-scale experiments or pilot studies.
At eqipped, we understand the importance of reliable lab supplies. That’s why we source this resin directly from Merck, a trusted name in chemical research. Whether you’re synthesizing therapeutic peptides or studying protein interactions, this resin delivers consistent results every time.
Upgrade your peptide synthesis workflow with H-Arg(Pbf)-2-Cltrt Resin. Order now and experience the difference in purity and performance.
Why This Resin Stands Out
Not all resins are created equal. H-Arg(Pbf)-2-Cltrt Resin offers several advantages over generic alternatives. The FMOC protection ensures compatibility with standard SPPS protocols, while the 2-Cltrt linker provides excellent loading capacity. This means fewer synthesis cycles and higher yields, saving you both time and resources.
Researchers in India often face challenges with inconsistent reagent quality. With this Merck resin, you can trust that each batch meets strict laboratory standards. The resin’s stability under typical storage conditions also means you can stock up without worrying about degradation.
For educators, this resin is an excellent teaching tool. Its predictable behavior makes it ideal for demonstrating SPPS techniques to students. The 5-gram pack size is sufficient for multiple class demonstrations, ensuring cost-effective learning.
Applications in Research and Education
H-Arg(Pbf)-2-Cltrt Resin is versatile and finds applications across various fields:
In pharmaceutical research, it’s used to synthesize peptide-based drugs and study their interactions. Academic labs rely on it for protein mimicry studies and enzyme-substrate research. Even in biotechnology, this resin helps in producing peptides for diagnostic assays.
For students, working with this resin provides hands-on experience with modern peptide synthesis techniques. The clear documentation from Merck makes it easier to troubleshoot and optimize protocols.
Need a dependable resin for your next peptide synthesis project? Buy H-Arg(Pbf)-2-Cltrt Resin online today and take your research to the next level.
Handling and Storage Guidelines
To maintain the resin’s integrity, store it in a cool, dry place away from direct sunlight. The container should be tightly sealed to prevent moisture absorption, which can affect performance. For long-term storage, consider using a desiccator.
When handling, use standard lab safety practices. While this resin is not classified as highly hazardous, it’s always good practice to wear gloves and work in a well-ventilated area. Avoid inhaling dust particles, and wash hands thoroughly after use.
Compatibility with SPPS Protocols
This resin is fully compatible with standard FMOC chemistry protocols. The Pbf protecting group on arginine is stable under typical synthesis conditions but can be easily removed during the final cleavage step. The 2-Cltrt linker allows for mild acidic cleavage, which is gentler on sensitive peptide sequences compared to other linkers.
If you’re new to SPPS, eqipped offers a range of complementary products, from coupling reagents to cleavage cocktails, to streamline your workflow. Pairing this resin with high-quality solvents and activators ensures the best possible results.
The typical loading capacity is around 0.5-1.0 mmol/g, but always refer to the certificate of analysis for batch-specific details.
Can this resin be used for C-terminal amide peptides?
Yes, the 2-Cltrt linker is suitable for synthesizing C-terminal amide peptides when used with appropriate cleavage conditions.
How should I store this resin to maximize shelf life?
Store in a desiccator at 2-8°C. Avoid exposure to moisture or extreme temperatures to prevent degradation.
Is this resin compatible with microwave-assisted peptide synthesis?
Yes, it can be used in microwave-assisted SPPS, but optimize conditions as excessive heat may affect the Pbf protecting group.
Where can I buy H-Arg(Pbf)-2-Cltrt Resin in India?
You can buy H-Arg(Pbf)-2-Cltrt Resin online from eqipped, a trusted supplier of lab-grade chemicals and reagents.
