Description
Specifications Table
| Product Name | Hctu Bulk | 8.51012.0500 | Merck |
|---|---|
| Quantity/Pack Size | 500 G |
| Form | Powder |
| Grade | Laboratory Grade |
| Application | Peptide Synthesis, Organic Synthesis |
Product Description
HCTU (2-(6-Chloro-1H-benzotriazole-1-yl)-1,1,3,3-tetramethylaminium hexafluorophosphate) is a highly efficient coupling reagent widely used in peptide synthesis. This bulk pack from Merck ensures consistent performance with minimal racemization, making it ideal for researchers and laboratories requiring reliable results.
Whether you’re synthesizing peptides for pharmaceutical research or academic projects, this HCTU bulk pack offers excellent solubility in common organic solvents like DMF and DCM. Its stability under standard laboratory conditions ensures long shelf life, reducing waste and repeat purchases.
For researchers looking to buy HCTU bulk online, eqipped provides authentic Merck products with verified purity. The 500g pack size is perfect for high-throughput labs, offering cost savings without compromising quality.
Key Applications
HCTU is particularly valued in solid-phase peptide synthesis (SPPS) due to its ability to minimize epimerization. It’s also used in the synthesis of complex organic molecules where high coupling efficiency is critical. Laboratories working on therapeutic peptides, enzyme substrates, or biochemical probes will find this reagent indispensable.
Handling and Storage
Store HCTU bulk in a cool, dry place away from moisture and direct sunlight. Always handle in a fume hood with appropriate PPE, as it may cause irritation upon contact with skin or eyes. For best results, use within the recommended shelf life period.
Why Researchers Prefer HCTU
Compared to other coupling reagents like HBTU or TATU, HCTU offers superior performance in challenging sequences. Its chloride leaving group provides faster reaction rates, while the tetramethylaminium counterion enhances solubility. This makes it a top choice for synthesizing difficult peptides with minimal side products.
When you buy HCTU bulk from eqipped, you’re getting a product trusted by leading research institutions. Our streamlined ordering process ensures you receive your supplies quickly, so your experiments stay on schedule.
FAQs
What is HCTU used for in peptide synthesis?
HCTU is a coupling reagent that activates carboxylic acids to form amide bonds, essential for building peptide chains. It’s preferred for its high efficiency and low racemization rates.
How does HCTU compare to HBTU?
HCTU generally offers faster coupling rates and better solubility than HBTU, making it ideal for automated peptide synthesizers and difficult sequences.
What safety precautions should I take when handling HCTU?
Wear nitrile gloves, safety goggles, and a lab coat. Work in a well-ventilated fume hood to avoid inhaling dust or vapors.
Can I use HCTU for large-scale peptide production?
Yes, the 500g bulk pack is designed for scale-up applications. Its stability and consistent performance make it suitable for industrial and academic large-scale synthesis.
How should I store HCTU to maintain its shelf life?
Keep the container tightly sealed in a desiccator at room temperature. Avoid exposure to humidity, which can degrade the reagent.
