Description
Specifications Table
| Product Name | FMOC-L-Arg(Pbf)-OH (N-α-Fmoc-Nω-Pbf-L-arginine) | TC1655 | CDH |
|---|---|
| Pack Size | 5 gm – 25 gm – 100 gm – 1 kg |
| Form | Powder |
| Grade | Peptide Synthesis Grade |
| Application | Solid-phase peptide synthesis, biochemical research |
Product Description
FMOC-L-Arg(Pbf)-OH is a high-purity protected arginine derivative widely used in peptide synthesis. The Fmoc (9-fluorenylmethoxycarbonyl) group protects the α-amino function, while the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group safeguards the guanidino side chain. This combination ensures stability during synthesis and easy deprotection under mild conditions.
Researchers and students rely on this compound for efficient solid-phase peptide synthesis (SPPS). Its high solubility in organic solvents like DMF and DCM makes it ideal for automated synthesizers. Whether you’re working on therapeutic peptides, biochemical studies, or academic projects, FMOC-L-Arg(Pbf)-OH delivers consistent results.
At eqipped, we source this product from trusted manufacturers to guarantee purity and performance. Each batch undergoes rigorous quality checks to meet international standards. Need bulk quantities for your lab? Contact us for customized packaging and competitive pricing.
The Pbf protecting group is particularly valuable in Fmoc-based synthesis, as it remains stable under acidic conditions used for Fmoc removal but can be easily cleaved with trifluoroacetic acid (TFA) during final deprotection. This makes it a preferred choice for synthesizing complex peptides with arginine residues.
For best results, store FMOC-L-Arg(Pbf)-OH in a cool, dry place away from moisture and light. Always use fresh, dry solvents to prevent side reactions. If you’re new to peptide synthesis, our team can guide you on proper handling and storage protocols.
FAQs
What is the shelf life of FMOC-L-Arg(Pbf)-OH?
When stored properly at -20°C, the product maintains stability for at least 24 months from the date of manufacture.
Can I use this for manual peptide synthesis?
Absolutely. While it’s commonly used in automated synthesizers, FMOC-L-Arg(Pbf)-OH works equally well for manual synthesis protocols.
What solvents work best for dissolving this compound?
DMF (dimethylformamide) and DCM (dichloromethane) are the most commonly used solvents for this protected amino acid.
Is this product suitable for therapeutic peptide production?
Yes, the high purity makes it suitable for research-grade therapeutic peptide synthesis, though additional quality controls may be needed for clinical applications.
How does the Pbf protecting group compare to other arginine protecting groups?
The Pbf group offers better stability during Fmoc deprotection compared to alternatives like Mtr or Pmc, making it ideal for complex peptide sequences.
