Description
Specifications Table
| Product Name | FMOC-Cys(Trt)-OH (N-Fmoc-S-trityl-L-cysteine) |
|---|---|
| Pack Size | 5 gm, 25 gm, 100 gm, 1 kg |
| Form | Powder |
| Grade | Reagent Grade |
| Application | Peptide synthesis, solid-phase synthesis, cysteine protection |
Product Description
FMOC-Cys(Trt)-OH, also known as N-Fmoc-S-trityl-L-cysteine, is a high-purity amino acid derivative widely used in peptide synthesis. The Trt (trityl) protecting group ensures stability during synthesis, making it ideal for solid-phase peptide synthesis (SPPS). Researchers and labs across India trust this compound for its reliability in protecting cysteine residues, preventing unwanted side reactions.
Whether you’re working on therapeutic peptides, biochemical studies, or custom peptide sequences, FMOC-Cys(Trt)-OH delivers consistent results. Its Fmoc protection allows for efficient coupling and deprotection steps, streamlining your synthesis workflow. For those looking to buy FMOC-Cys(Trt)-OH online, eqipped offers competitive pricing and fast shipping across India.
Need high-quality FMOC-Cys(Trt)-OH for your research? Shop now for bulk discounts and lab-ready packaging.
Why FMOC-Cys(Trt)-OH is Essential for Peptide Synthesis
Cysteine is a critical amino acid in peptide chemistry, but its thiol group is highly reactive. FMOC-Cys(Trt)-OH solves this by temporarily blocking the thiol with a trityl group, allowing controlled synthesis. Once the peptide chain is complete, the Trt group can be easily removed under mild acidic conditions, restoring the free thiol.
This makes FMOC-Cys(Trt)-OH a staple in labs working on:
- Therapeutic peptides (e.g., insulin analogs, antimicrobial peptides)
- Protein engineering and modification
- Bioconjugation studies
- Structural biology research
Looking for a trusted FMOC-Cys(Trt)-OH supplier in India? eqipped provides lab-grade purity with batch-to-batch consistency.
How to Use FMOC-Cys(Trt)-OH in SPPS
1. Coupling Step: Activate FMOC-Cys(Trt)-OH using standard coupling reagents like HATU or DIC/HOBt.
2. Deprotection: Remove the Fmoc group with piperidine in DMF.
3. Final Deprotection: Cleave the Trt group using TFA (trifluoroacetic acid) with scavengers like triisopropylsilane (TIS).
Always follow your lab’s safety protocols when handling acids and organic solvents.
Storage and Handling
Store FMOC-Cys(Trt)-OH in a cool, dry place away from moisture. Keep containers tightly sealed to prevent degradation. For long-term storage, consider desiccants or inert gas purging.
Risk Note: This product is for research use only. Not for human consumption. Handle with appropriate PPE (gloves, goggles, lab coat).
FAQs
What is FMOC-Cys(Trt)-OH used for?
It’s primarily used in peptide synthesis to protect cysteine’s thiol group during chain assembly, preventing oxidation or side reactions.
How do I remove the Trt protecting group?
The Trt group is cleaved using mild acidic conditions, typically TFA with scavengers like TIS or water.
Is FMOC-Cys(Trt)-OH compatible with Fmoc chemistry?
Yes, it’s designed for Fmoc-based solid-phase peptide synthesis (SPPS) and integrates seamlessly with standard protocols.
What pack sizes are available?
eqipped offers FMOC-Cys(Trt)-OH in 5 gm, 25 gm, 100 gm, and 1 kg packs to suit small-scale and bulk needs.
Can I buy FMOC-Cys(Trt)-OH online in India?
Absolutely! eqipped provides fast, reliable delivery across India with secure packaging for lab chemicals.
