Description

Specifications Table

Product Name – Heptanesulfonic acid sodium salt, monohydrate HPLC
Quantity/Pack Size – 25 g
Form – Solid (powder/crystals)
Grade – HPLC (≥98% purity)
Application – Ion-pairing reagent, chromatographic separations

Product Overview

Heptanesulfonic acid sodium salt monohydrate is a high-purity, HPLC-grade reagent designed for demanding chromatographic applications. This compound serves as an effective ion-pairing agent, facilitating the separation of polar and ionic compounds in reversed-phase HPLC systems. Its sodium salt form ensures enhanced solubility in aqueous mobile phases while maintaining stability across a wide pH range. The monohydrate structure provides consistent performance, minimizing batch-to-batch variability. With a purity of ≥98%, this reagent meets stringent analytical requirements, delivering sharp, reproducible peaks in chromatographic analyses. The compound’s long hydrophobic chain (C7) offers optimal retention for a broad spectrum of analytes, making it versatile for complex sample matrices. Its low UV absorbance at common detection wavelengths ensures minimal interference with analyte signals. The solid form allows for precise weighing and easy preparation of mobile phase solutions. This reagent is particularly valued for its ability to improve peak symmetry and resolution in separations involving basic or acidic compounds.

FAQs

1. What is the primary function of heptanesulfonic acid sodium salt in HPLC?

It acts as an ion-pairing reagent that neutralizes charged analytes, enabling their retention and separation on reversed-phase columns through hydrophobic interactions.

2. How does this compare to shorter-chain sulfonic acids like pentanesulfonic acid?

Heptanesulfonic acid provides stronger hydrophobic interactions due to its longer carbon chain, resulting in better retention of highly polar compounds compared to shorter-chain alternatives.

3. What mobile phase pH range works best with this reagent?

The reagent performs optimally in the pH range of 2.5-4.5, where it remains fully ionized while maintaining column stability and analyte retention.

4. Can this be used with mass spectrometry detection?

While possible, its non-volatile nature may cause ion suppression; alternative volatile ion-pairing reagents are typically preferred for LC-MS applications.