Description

Specifications Table

Product Name – 1-Hexanesulfonic acid sodium salt, monohydrate
Quantity/Pack Size – 25 g
Form – Crystalline powder
Grade – HPLC (≥99.0%)
Application – Ion-pair chromatography, reversed-phase HPLC

Product Overview

1-Hexanesulfonic acid sodium salt monohydrate is a high-purity ion-pair reagent specifically designed for reversed-phase high-performance liquid chromatography (HPLC). This HPLC-grade compound ensures minimal UV absorbance interference, making it ideal for sensitive analytical applications where baseline stability is critical. The sodium salt form enhances solubility in aqueous mobile phases, providing consistent retention times for ionic analytes. Its monohydrate structure maintains stability under standard laboratory conditions while preserving chromatographic performance. The reagent undergoes rigorous quality control to guarantee lot-to-lot reproducibility, with residual impurities kept below detectable limits for HPLC applications. The crystalline powder format allows for precise weighing and easy dissolution in mobile phase preparation. Compatible with most C18 and C8 stationary phases, this reagent facilitates the separation of polar compounds that would otherwise elute too quickly in standard reversed-phase systems. The 99.0% minimum purity specification ensures reliable results in quantitative analyses where accuracy is paramount.

FAQs

1. What is the typical working concentration range for this reagent in HPLC mobile phases?

Most applications use concentrations between 1-10 mM, though optimal levels depend on the specific analytes and column chemistry being employed.

2. How does this compare to shorter-chain alkyl sulfonic acids in terms of retention behavior?

The hexyl chain provides stronger hydrophobic interactions than butyl or propyl analogs, resulting in greater retention of ionic compounds without requiring excessively high concentrations.

3. What pH range is compatible with this ion-pair reagent?

The reagent remains stable and effective across pH 2-7, though extreme pH values may affect both the reagent’s performance and column lifetime.

4. Are there any known column compatibility issues with this reagent?

While generally compatible with most reversed-phase columns, prolonged use at high concentrations may accelerate degradation of silica-based stationary phases.

5. What storage conditions are recommended to maintain product integrity?

Store in a tightly sealed container at room temperature, protected from moisture and direct light to prevent hydration changes or potential degradation.