Specifications Table

Product Name – (Trimethylsilyl)imidazole
Quantity/Pack Size – 100 g
Form – Solid
Grade – Laboratory Grade
Application – Silylation reagent for analytical chemistry

Product Overview

(Trimethylsilyl)imidazole is a highly efficient silylating reagent widely used in analytical chemistry for derivatization processes. This laboratory-grade compound exhibits exceptional reactivity with hydroxyl, carboxyl, and amine groups, making it ideal for gas chromatography-mass spectrometry (GC-MS) applications. The reagent’s high purity ensures minimal background interference, while its stability under standard lab conditions guarantees consistent performance. Its solid form allows for easy handling and precise weighing, reducing the risk of contamination or accidental spillage. The compound’s molecular structure, featuring a trimethylsilyl group bonded to an imidazole ring, provides enhanced nucleophilicity compared to traditional silylating agents. This structural advantage translates to faster reaction kinetics and improved derivatization yields. The reagent is particularly effective in converting polar functional groups into their trimethylsilyl derivatives, thereby increasing volatility and thermal stability for chromatographic analysis. Its compatibility with a wide range of solvents further enhances its versatility in various laboratory protocols. The product’s consistent quality and reliable performance make it a preferred choice for researchers requiring reproducible results in their analytical workflows.

FAQs

1. What is the primary function of (Trimethylsilyl)imidazole in laboratory applications?

It serves as a silylating agent that converts active hydrogen-containing functional groups into their trimethylsilyl derivatives, enhancing volatility for chromatographic analysis.

2. How should this reagent be stored to maintain its stability?

Store in a cool, dry place away from moisture and incompatible substances. Keep the container tightly sealed when not in use to prevent hydrolysis.

3. What safety precautions should be taken when handling this chemical?

Wear appropriate personal protective equipment including gloves, goggles, and lab coat. Work in a well-ventilated area or fume hood to avoid inhalation of vapors.

4. Is this reagent compatible with common laboratory solvents?

Yes, it shows good solubility in most organic solvents including dichloromethane, acetonitrile, and pyridine, making it versatile for various reaction conditions.

5. What distinguishes this reagent from other silylating agents?

Its imidazole leaving group provides superior nucleophilicity compared to traditional agents, resulting in faster reaction times and higher derivatization efficiency.