Description
Specifications Table
Product Name – 1-Hexanesulfonic acid, sodium salt HPLC
Quantity/Pack Size – 25 g
Form – Solid (Powder/Crystalline)
Grade – HPLC
Application – Ion-pair chromatography, reverse-phase HPLC
Product Overview
1-Hexanesulfonic acid sodium salt is a high-purity ion-pairing reagent specifically designed for HPLC applications, ensuring reliable and reproducible separations of ionic compounds. This HPLC-grade reagent exhibits low UV absorbance, making it ideal for sensitive detection methods without interfering with analyte signals. Its consistent ionic strength and solubility in aqueous and organic solvents enhance peak resolution, particularly for polar and ionizable analytes. The sodium salt form provides stability and compatibility with a wide range of mobile phases, reducing the risk of column degradation or baseline drift. Manufactured under stringent quality controls, this reagent meets the demands of high-performance liquid chromatography, delivering sharp, well-defined peaks for accurate quantification. Its low impurity profile minimizes background noise, ensuring high signal-to-noise ratios in analytical workflows. Whether used in gradient or isocratic elution, this reagent maintains robust performance across varying pH and temperature conditions, making it a versatile choice for complex separations.
FAQs
1. What is the primary function of 1-Hexanesulfonic acid sodium salt in HPLC?
It acts as an ion-pairing reagent to improve the retention and separation of ionic or polar compounds in reverse-phase HPLC by forming neutral ion pairs.
2. Is this reagent compatible with mass spectrometry (MS) detection?
While it can be used, its non-volatile nature may require additional cleanup or alternative reagents like trifluoroacetic acid for optimal MS compatibility.
3. How should this product be stored to maintain stability?
Store in a tightly sealed container at room temperature, protected from moisture and light to prevent degradation or hydration.
4. Can this be used as a substitute for heptanesulfonic acid in HPLC methods?
Yes, but retention times may vary due to differences in alkyl chain length; method revalidation is recommended when switching reagents.
5. What solvents is this reagent soluble in for mobile phase preparation?
It is freely soluble in water and methanol, with moderate solubility in acetonitrile, allowing flexibility in mobile phase composition.
