Description
Specifications Table
Product Name – Acetic Acid, Glacial HPLC
Quantity/Pack Size – 2.5 L
Form – Liquid (Glacial)
Grade – HPLC
Application – Chromatography, solvent preparation, analytical reagents
Product Overview
This HPLC-grade glacial acetic acid is a high-purity solvent designed for demanding laboratory applications where minimal impurities are critical. With a non-volatile residue content of ≤0.0005%, it ensures accurate results in high-performance liquid chromatography (HPLC) and other sensitive analytical techniques. The glacial form (99.7%+ purity) eliminates water content, preventing dilution effects in reactions or separations. Its low UV absorbance and negligible metal ion contamination make it ideal for spectroscopic analysis and trace metal studies. The acid’s consistent lot-to-lot purity is verified through rigorous quality control, including GC and ICP-MS testing, to meet international pharmacopeia standards. Packaged in amber glass bottles to prevent photodegradation, it maintains stability during storage and transport. The acid’s versatility extends to pH adjustment in biological buffers and protein precipitation protocols, though its primary strength lies in chromatographic applications where baseline stability is paramount.
FAQs
1. What is the difference between glacial acetic acid and regular acetic acid?
Glacial acetic acid refers to the water-free (99.7%+ purity) form, while regular acetic acid typically contains 5-8% water. The glacial version is essential for applications requiring precise concentrations and minimal interference from water molecules.
2. Can this HPLC-grade acetic acid be used for LC-MS applications?
Yes, this grade is suitable for LC-MS as it meets the low impurity requirements for mass spectrometry. The ≤0.0005% non-volatile residue specification ensures minimal ion suppression effects during analysis.
3. What type of container is recommended for long-term storage?
Store in the original amber glass bottle with a PTFE-lined cap to prevent contamination and photodegradation. Avoid plastic containers as acetic acid can leach additives over time.
4. How does the purity of this product compare to ACS-grade acetic acid?
HPLC-grade acetic acid has stricter specifications for UV absorbance and non-volatile residues compared to ACS grade. While ACS grade meets general analytical needs, HPLC grade is optimized for chromatographic baseline stability.
5. What safety precautions should be taken when handling glacial acetic acid?
Always use in a fume hood with proper PPE (nitrile gloves, goggles, lab coat). The concentrated form can cause severe skin burns and respiratory irritation. Neutralize spills with sodium bicarbonate before cleanup.
