Description
Specifications Table
Product Name – Methyl tert-butyl ether HPLC
Quantity/Pack Size – 4 L
Form – Liquid
Grade – HPLC (≥99.8%)
Application – Chromatography, solvent extraction, organic synthesis
Product Overview
Methyl tert-butyl ether (MTBE) HPLC grade is a high-purity, non-polar solvent engineered for demanding chromatographic applications. With a minimum purity of 99.8%, this reagent-grade ether ensures minimal interference in UV detection, making it ideal for high-performance liquid chromatography (HPLC) and gas chromatography (GC) workflows. Its low water content (<0.05%) and absence of stabilizers prevent baseline drift or ghost peaks, guaranteeing reproducible results. The solvent’s volatility (boiling point: 55°C) enables rapid evaporation, reducing sample preparation time, while its chemical stability ensures long-term storage integrity. Compatible with most stationary phases, MTBE HPLC grade is particularly effective for separating non-polar to moderately polar compounds. Its low viscosity (0.364 cP at 20°C) minimizes column backpressure, improving resolution and extending column lifespan. Packaged in amber glass bottles to prevent photodegradation, this solvent meets ACS and Reag. Ph Eur specifications, ensuring compliance with international lab standards.
FAQs
1. What is the shelf life of HPLC-grade MTBE when stored properly?
When stored in a tightly sealed container at room temperature (15–25°C) away from direct sunlight and moisture, unopened HPLC-grade MTBE retains its specified purity for up to 24 months from the date of manufacture. Opened bottles should be used within 6 months to prevent contamination or evaporation.
2. Can this MTBE be used as a substitute for hexane in normal-phase chromatography?
Yes, MTBE is a viable alternative to hexane in normal-phase chromatography due to its similar eluotropic strength (P’ = 2.7 vs. hexane’s 0.1) and lower toxicity. However, its slightly higher polarity may require adjustments to gradient conditions or mobile phase ratios for optimal separation.
3. Does this product contain any stabilizers like BHT?
No, this HPLC-grade MTBE is free from stabilizers such as BHT (butylated hydroxytoluene) or other additives, which ensures minimal background interference in sensitive analytical techniques like UV-Vis or mass spectrometry.
4. What precautions should be taken when handling MTBE?
MTBE is highly flammable (flash point: -28°C) and should be handled in a fume hood with proper ventilation. Use nitrile or neoprene gloves, safety goggles, and a lab coat to avoid skin/eye contact. Avoid inhalation of vapors, and store away from ignition sources or oxidizing agents.
5. How does the UV cutoff of this MTBE compare to other common HPLC solvents?
The UV cutoff for this MTBE is <210 nm, which is lower than acetonitrile (190 nm) but higher than methanol (205 nm) or water (190 nm). This makes it suitable for UV detection down to 210 nm, though gradient methods may require solvent matching for baseline stability.
