Description
Specifications Table
Product Name – 1-Octanesulfonic acid sodium salt HiPerSolv CHROMANORM® for HPLC
Quantity/Pack Size – 100 g
Form – Solid (powder/crystals)
Grade – HiPerSolv CHROMANORM® (HPLC)
Application – Ion-pair reagent for reverse-phase HPLC, LC-MS
Product Overview
1-Octanesulfonic acid sodium salt HiPerSolv CHROMANORM® is a high-purity ion-pairing reagent specifically designed for high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) applications. This HPLC-grade salt ensures minimal UV absorbance, making it ideal for sensitive detection methods where baseline stability is critical. Its high solubility in aqueous and organic solvents allows for seamless integration into mobile phases, enhancing retention and selectivity for ionic or polar analytes. The HiPerSolv CHROMANORM® certification guarantees lot-to-lot consistency, low impurity levels, and compliance with stringent chromatographic standards. The sodium salt form provides improved stability compared to the free acid, reducing degradation risks during storage or prolonged use. Its hydrophobic octyl chain enables effective ion-pair formation with basic compounds, improving peak symmetry and resolution in reverse-phase separations. This reagent is particularly valuable for complex matrices where traditional buffers fail to achieve adequate retention. The 100 g pack size offers cost-effective scalability for both routine and high-throughput laboratories.
FAQs
1. What is the shelf life of 1-Octanesulfonic acid sodium salt HiPerSolv CHROMANORM®?
The product remains stable for 24 months from the date of manufacture when stored unopened in its original packaging at room temperature, protected from moisture and light. After opening, use within 6 months for optimal performance.
2. Can this reagent be used with LC-MS systems?
Yes, this HiPerSolv CHROMANORM® grade is compatible with LC-MS applications. Its ultra-low impurity profile minimizes background noise and ion suppression, ensuring reliable mass spectrometric detection without signal interference.
3. How does this compare to heptanesulfonic acid sodium salt?
The octyl chain (C8) in this reagent provides stronger hydrophobic interactions compared to heptanesulfonic acid (C7), resulting in improved retention for highly polar or basic analytes. It’s particularly effective for compounds that elute too early with shorter-chain ion-pairing agents.
4. What solvents are recommended for preparing mobile phases?
The salt dissolves readily in water, methanol, and acetonitrile. For typical HPLC applications, prepare a 5–20 mM aqueous solution and adjust the pH to 2.5–3.5 with phosphoric acid or formic acid before mixing with organic modifiers.
5. Is this product suitable for gradient elution methods?
Yes, it performs well in gradient elution due to its consistent solubility across varying solvent compositions. However, ensure the mobile phase is filtered and degassed to prevent baseline drift caused by reagent precipitation during gradient transitions.
