Description
Specifications Table
Product Name – Acetic acid, 0.1% in water HiPerSolv CHROMANORM® for LC-MS
Quantity/Pack Size – 1 L
Form – Liquid (aqueous solution)
Grade – HiPerSolv CHROMANORM® (LC-MS grade)
Application – Mobile phase modifier, protein/peptide analysis, mass spectrometry
Product Overview
Acetic acid, 0.1% in water HiPerSolv CHROMANORM® is a high-purity solvent specifically formulated for liquid chromatography-mass spectrometry (LC-MS) applications. This ultra-low background solution ensures minimal interference with analyte detection, making it ideal for sensitive analytical workflows. The HiPerSolv CHROMANORM® grade guarantees consistent lot-to-lot performance with stringent quality control measures, including ultra-low metal ion content and optimized pH stability. The 0.1% concentration provides an optimal balance between ionization efficiency and chromatographic resolution, particularly for peptide and protein analysis. Its water-based formulation eliminates the need for additional dilution in most applications, reducing preparation time while maintaining reproducibility. The solution is filtered through 0.22 µm membranes to ensure particulate-free performance, protecting delicate LC-MS instrumentation from potential contamination. This product meets the rigorous requirements of modern analytical laboratories, offering reliable results for both qualitative and quantitative analyses.
FAQs
1. What makes HiPerSolv CHROMANORM® grade acetic acid different from standard laboratory-grade acetic acid?
The HiPerSolv CHROMANORM® grade undergoes additional purification processes to achieve ultra-low levels of contaminants, including metal ions and organic impurities, which are critical for LC-MS applications where even trace amounts can interfere with detection.
2. Can this solution be used as a mobile phase additive without further dilution?
Yes, the 0.1% concentration is pre-optimized for direct use as a mobile phase modifier in most LC-MS applications, though some protocols may require minor adjustments based on specific analyte requirements.
3. How does the water quality in this solution impact LC-MS performance?
The water used in this formulation meets Type I reagent grade specifications, with resistivity of 18.2 MΩ·cm and total organic carbon (TOC) levels below 5 ppb, ensuring minimal background noise in mass spectrometry.
4. What is the typical shelf life of this product when stored properly?
When stored at room temperature in its original tightly sealed container, this solution maintains its specified purity for at least 24 months from the date of manufacture.
5. Are there any compatibility concerns with common LC-MS column chemistries?
This solution is compatible with most reversed-phase columns, including C18, C8, and phenyl-hexyl phases, though it’s recommended to verify compatibility with specialty columns like HILIC or ion-exchange resins.
