Description
Specifications Table
Product Name – Chlorotrimethylsilane, 98%, AcroSeal®
Quantity/Pack Size – 100ML
Form – Liquid
Grade – 98%
Application – Silylation reagent, protecting groups
Product Overview
Chlorotrimethylsilane is a high-purity (98%) organosilicon compound widely used in organic synthesis for silylation reactions. The AcroSeal® packaging ensures maximum protection against moisture, preserving the reagent’s reactivity and extending shelf life. This compound is highly effective for converting alcohols, amines, and carboxylic acids into their corresponding trimethylsilyl derivatives, which are more volatile and easier to analyze via gas chromatography. The liquid form allows for precise dosing, making it suitable for both small-scale and bulk applications. Its low boiling point (57°C) enables easy removal post-reaction, simplifying purification processes. The reagent is compatible with most organic solvents, including dichloromethane, THF, and hexane, but reacts violently with water, necessitating careful handling under inert conditions. The AcroSeal® bottle features a secure cap to prevent accidental exposure to atmospheric moisture, ensuring consistent performance in critical applications.
FAQs
1. What is the primary use of chlorotrimethylsilane in lab settings?
It is primarily used as a silylating agent to protect functional groups like alcohols, amines, and carboxylic acids during synthesis.
2. Is this product compatible with glassware, or does it require special containers?
It is compatible with standard glassware, but ensure all equipment is dry and moisture-free before use.
3. What alternatives exist if chlorotrimethylsilane is unavailable?
Alternatives include tert-butyldimethylsilyl chloride (TBSCl) or triethylsilyl chloride, though reactivity may vary.
4. How should chlorotrimethylsilane be stored for long-term stability?
Store in a tightly sealed AcroSeal® bottle under inert gas (argon/nitrogen) at room temperature, away from moisture.
5. Does this product require any special handling precautions?
Yes, it is moisture-sensitive and corrosive. Handle in a fume hood with gloves and avoid contact with water or skin.
