Specifications Table

Product Name – 1-Propanol, for HPLC
Quantity/Pack Size – 1LT, 2.5LT
Form – Liquid
Grade – HPLC
Application – Chromatography, solvent extraction, sample preparation

Product Overview

1-Propanol, HPLC-grade, is a high-purity solvent designed for demanding chromatographic applications where precision and consistency are critical. This reagent-grade alcohol offers exceptional clarity and low UV absorbance, making it ideal for high-performance liquid chromatography (HPLC) systems. Its ultra-low impurity profile ensures minimal interference, delivering reliable baseline stability and sharp peak resolution. The solvent undergoes rigorous purification processes to eliminate trace contaminants, including metals, non-volatile residues, and particulate matter, which could compromise analytical results. With a boiling point of 97°C and miscibility in water and organic solvents, it serves as a versatile eluent and extraction medium. The HPLC-grade certification guarantees compliance with strict quality standards, ensuring reproducibility in quantitative and qualitative analyses. Its low reactivity and high evaporative efficiency further enhance its suitability for sample preparation and mobile phase applications. Packaged in amber glass bottles to prevent photodegradation, this 1-Propanol variant maintains its integrity during storage and handling, providing researchers with a dependable solvent for critical lab procedures.

FAQs

1. What is the difference between HPLC-grade and reagent-grade 1-Propanol?

HPLC-grade 1-Propanol undergoes additional purification steps to remove UV-absorbing impurities and particulate matter, which are not as strictly controlled in reagent-grade variants. This makes it specifically suited for chromatographic applications where baseline stability and peak resolution are essential.

2. Can this 1-Propanol be used as a substitute for methanol or ethanol in HPLC?

While 1-Propanol can replace methanol or ethanol in certain HPLC methods, its higher viscosity and different elution strength may require adjustments to flow rates, gradient profiles, or mobile phase compositions. Always validate method compatibility before substitution.

3. How should HPLC-grade 1-Propanol be stored to maintain its purity?

Store the solvent in its original amber glass container, tightly sealed, at room temperature (15–25°C). Avoid exposure to direct sunlight, moisture, or extreme temperatures, as these can degrade purity or introduce contaminants.

4. Is this 1-Propanol compatible with all HPLC column types?

The solvent is generally compatible with reversed-phase columns (e.g., C18, C8) and normal-phase silica columns. However, prolonged use with certain stationary phases, like ion-exchange or size-exclusion columns, may require compatibility testing due to potential interactions.

5. What precautions should be taken when handling HPLC-grade 1-Propanol?

Wear appropriate PPE, including nitrile gloves and safety goggles, as 1-Propanol is flammable and can cause skin/eye irritation. Use in a well-ventilated area or fume hood to avoid inhalation exposure, and keep away from ignition sources.