Specifications Table
Product Name – 3-Butenylmagnesium bromide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid (THF solution)
Grade – Reagent
Application – Grignard reagent for organic synthesis
Product Overview
3-Butenylmagnesium bromide is a highly reactive Grignard reagent supplied as a 0.5M solution in anhydrous tetrahydrofuran (THF) under nitrogen atmosphere in AcroSeal® packaging. This organomagnesium compound is widely utilized in organic synthesis for carbon-carbon bond formation, particularly in the preparation of allylic and homoallylic alcohols via nucleophilic addition to carbonyl compounds. The THF solvent ensures optimal solubility and reactivity while maintaining stability during storage. The AcroSeal® technology provides an airtight, moisture-resistant seal that preserves reagent integrity and extends shelf life. This solution is standardized at 0.5M concentration to offer precise stoichiometric control in synthetic applications. The reagent’s allylic structure enables unique reactivity patterns compared to simpler alkyl Grignard reagents, making it valuable for constructing complex molecular frameworks. Proper handling under inert atmosphere is recommended to maintain reactivity and prevent decomposition.
FAQs
1. What is the typical concentration range for 3-Butenylmagnesium bromide solutions?
The standard concentration for this reagent is 0.5M in THF, which balances reactivity with handling convenience.
2. How should this reagent be stored to maintain stability?
Store at 2-8°C under nitrogen atmosphere, keeping the container tightly sealed to prevent moisture and oxygen exposure.
3. What safety precautions are essential when handling this solution?
Use in a well-ventilated fume hood with proper PPE, as it’s highly flammable and reacts violently with water.
4. Can this reagent be used in place of allylmagnesium bromide?
While similar, the butenyl structure provides different regioselectivity in certain reactions compared to allyl reagents.
5. What’s the significance of the AcroSeal® packaging?
The AcroSeal® system ensures airtight, moisture-resistant storage that preserves reagent quality during extended storage periods.