Description
Specifications Table
Product Name – Tetrabutylammonium hydroxide, 1M solution in methanol, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid (1M solution in methanol)
Grade – AcroSeal® (high-purity, lab-grade)
Application – Phase-transfer catalysis, organic synthesis, analytical chemistry
Product Overview
Tetrabutylammonium hydroxide, supplied as a 1M solution in methanol under the AcroSeal® brand, is a high-purity quaternary ammonium base widely used in organic synthesis and phase-transfer catalysis. The methanol-based solution ensures stability and ease of handling, making it suitable for applications requiring a strong, non-nucleophilic base. Its AcroSeal® packaging guarantees minimal exposure to moisture and contaminants, preserving reagent integrity for consistent performance in lab-scale reactions. The 1M concentration provides a balanced strength for efficient catalysis without excessive reagent waste. This solution is particularly valued in processes involving deprotonation, alkylation, and condensation reactions, where precise control over basicity is critical. The methanol solvent enhances solubility for organic substrates, ensuring homogeneous reaction conditions. For researchers and chemists, this reagent offers reliability in reproducibility and scalability, whether used in small-scale experiments or preparative chemistry.
FAQs
1. What is the shelf life of tetrabutylammonium hydroxide 1M in methanol?
The solution remains stable for 12–24 months when stored unopened in its original AcroSeal® packaging at room temperature, away from direct sunlight and moisture. Always check the label for the manufacturer’s expiry date.
2. Can this solution be used as a phase-transfer catalyst in aqueous-organic biphasic systems?
Yes, tetrabutylammonium hydroxide is highly effective as a phase-transfer catalyst due to its ability to solubilize inorganic anions in organic solvents, facilitating reactions between aqueous and organic phases.
3. Are there any compatibility issues with glass or plastic containers?
The methanol-based solution is compatible with glass containers and most high-density polyethylene (HDPE) or polypropylene (PP) plastic bottles. Avoid prolonged storage in low-grade plastics, as methanol may cause degradation.
4. What precautions should be taken when handling this reagent?
Wear nitrile gloves, safety goggles, and a lab coat, as the solution is corrosive and flammable. Work in a fume hood to avoid inhalation of methanol vapors, and ensure proper ventilation.
5. Is this the same as tetrabutylammonium fluoride (TBAF)?
No, tetrabutylammonium hydroxide is a strong base, while TBAF is a fluoride source. They serve different roles—hydroxide is used for deprotonation, whereas TBAF is typically employed for desilylation reactions.
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