Description
Specifications Table
Product Name – Tetrapropylammonium hydroxide, 10% in water
Quantity/Pack Size – 100GR, 500GR
Form – Liquid (aqueous solution)
Grade – AR (Analytical Reagent)
Application – Phase-transfer catalyst, organic synthesis
Product Overview
Tetrapropylammonium hydroxide (TPAOH), supplied as a 10% aqueous solution, is a quaternary ammonium base widely used in organic synthesis and phase-transfer catalysis. This AR-grade solution ensures high purity and consistent performance, making it suitable for applications requiring strong, non-nucleophilic bases. The 10% concentration provides an optimal balance between reactivity and ease of handling, reducing the need for dilution while maintaining stability. The solution is stable under normal storage conditions but should be protected from moisture and extreme temperatures to prevent degradation. Its compatibility with organic solvents and water makes it versatile for biphasic reaction systems. The absence of nucleophilic properties allows selective deprotonation without competing side reactions, ensuring cleaner product formation. This solution is particularly effective in promoting reactions involving weak acids or neutral substrates where traditional bases fail. Proper handling with standard lab safety measures is recommended due to its corrosive nature.
FAQs
1. What is the shelf life of 10% TPAOH solution?
When stored unopened in a cool, dry place, the solution remains stable for 12–24 months. Check for precipitation or color change before use.
2. Can this solution be used in non-aqueous reactions?
Yes, but evaporation of water may be required for anhydrous conditions. The quaternary ammonium structure remains active in organic solvents.
3. What safety precautions are necessary when handling TPAOH?
Wear nitrile gloves, goggles, and work in a fume hood. Avoid inhalation and skin contact due to its corrosive alkaline nature.
4. Is this solution compatible with glassware?
Yes, but prolonged contact with glass at high temperatures may cause etching. Use PTFE-lined caps for long-term storage.
5. How does TPAOH compare to tetrabutylammonium hydroxide (TBAOH)?h4>
TPAOH offers higher thermal stability and lower nucleophilicity, making it preferable for reactions sensitive to steric hindrance.
