Description

Specifications Table

Product Name – 3,5-Bis(trifluoromethyl)phenylmagnesium bromide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 100ML
Form – Liquid (THF solution)
Grade – Laboratory grade
Application – Organic synthesis, Grignard reactions

Product Overview

3,5-Bis(trifluoromethyl)phenylmagnesium bromide is a specialized Grignard reagent supplied as a 0.5M solution in tetrahydrofuran (THF), designed for high-efficiency organic synthesis. This reagent features a bis(trifluoromethyl)phenyl group, which enhances its reactivity and selectivity in nucleophilic addition and substitution reactions. The THF solvent ensures stability and solubility, making it ideal for laboratory applications requiring precise control over reaction conditions. The AcroSeal® packaging guarantees airtight containment, preventing moisture-induced degradation and maintaining reagent integrity. This solution is particularly valuable for synthesizing complex organic molecules, where steric and electronic effects play a critical role. Its consistent molar concentration simplifies stoichiometric calculations, ensuring reproducibility in experimental setups. The reagent’s high purity minimizes side reactions, improving yield and product quality.

FAQs

1. What is the shelf life of 3,5-bis(trifluoromethyl)phenylmagnesium bromide in THF?

When stored unopened in its original AcroSeal® packaging at recommended temperatures, this reagent typically retains its reactivity for 12–24 months. Always check the label for the exact expiration date.

2. Can this reagent be used in reactions requiring anhydrous conditions?

Yes, the THF solvent is anhydrous, and the AcroSeal® packaging prevents moisture contamination, making it suitable for moisture-sensitive reactions.

3. Are there any special handling precautions for this Grignard reagent?

This reagent is highly reactive with water and air. Handle under an inert atmosphere (e.g., nitrogen or argon) and use dry glassware to avoid decomposition.

4. What alternatives exist if this specific Grignard reagent is unavailable?

Alternatives may include other trifluoromethyl-substituted phenylmagnesium bromides or similar Grignard reagents with electron-withdrawing groups, though reactivity profiles may vary.