Description
Specifications Table
Product Name – Boron Tribromide Dimethyl Sulfide, 1M Solution in Methylene Chloride, AcroSeal®
Quantity/Pack Size – 100ML
Form – Liquid solution
Grade – AcroSeal® (anhydrous, high-purity)
Application – Demethylation, deprotection, and selective bromination reactions
Product Overview
Boron Tribromide Dimethyl Sulfide 1M solution in methylene chloride (CH₂Cl₂) is a specialized reagent designed for high-efficiency demethylation and deprotection reactions in organic synthesis. The AcroSeal® packaging ensures moisture-sensitive stability, preserving the reagent’s reactivity and purity for critical applications. This solution eliminates the need for handling neat boron tribromide, offering enhanced safety and convenience without compromising performance. The methylene chloride solvent provides optimal solubility for boron tribromide while maintaining compatibility with standard laboratory glassware. Its anhydrous nature prevents side reactions, making it ideal for sensitive transformations where water contamination could disrupt yields. The 1M concentration balances reactivity with ease of dosing, reducing measurement errors in small-scale or high-precision workflows. Store under inert gas and tightly sealed to maintain integrity.
FAQs
1. What is the shelf life of this Boron Tribromide solution when stored properly?
When stored under nitrogen or argon in its original AcroSeal® packaging at 2–8°C, the solution remains stable for up to 12 months from the date of manufacture. Always verify the label for batch-specific expiration.
2. Can this solution be used directly for deprotection of methyl ethers?
Yes, the 1M concentration is optimized for direct use in demethylation reactions, including cleavage of methyl ethers from phenols or aromatic compounds, without requiring further dilution in most protocols.
3. Is this solution compatible with standard Schlenk line techniques?
The AcroSeal® bottle is designed for seamless integration with Schlenk lines or glove boxes, allowing anaerobic transfer via syringe or cannula to maintain inert conditions during handling.
4. What precautions should be taken when disposing of residual solution?
Neutralize excess reagent with slow addition to a cold aqueous sodium bicarbonate solution (10% w/v) in a well-ventilated fume hood, followed by appropriate halogenated waste disposal as per local regulations.
5. How does the dimethyl sulfide complex affect the reactivity compared to neat boron tribromide?
The dimethyl sulfide complex moderates the Lewis acidity, reducing the risk of over-bromination or side reactions while maintaining sufficient reactivity for most demethylation applications, offering better selectivity in sensitive substrates.
