Description
Specifications Table
Product Name – Chlorodiisopropylphosphine, 96%, AcroSeal®
Quantity/Pack Size – 50ML
Form – Liquid
Grade – 96%
Application – Organophosphorus synthesis, ligand preparation
Product Overview
Chlorodiisopropylphosphine (96% purity) is a highly reactive organophosphorus compound supplied in a 50ML AcroSeal® bottle to prevent moisture contamination and oxidation. This colorless to pale yellow liquid is widely utilized as a key building block in the synthesis of phosphine ligands, phosphonates, and other phosphorus-containing compounds. The AcroSeal® packaging ensures long-term stability by minimizing exposure to air and humidity, preserving the reagent’s reactivity. With a boiling point of approximately 60-62°C at 12 mmHg, this compound requires careful handling under inert conditions (nitrogen or argon) to maintain purity. Its high reactivity makes it suitable for nucleophilic substitutions, forming P-C bonds in organic synthesis. The 96% grade balances purity and cost-effectiveness, making it ideal for research-scale applications where trace impurities are tolerable. Store under refrigeration (2-8°C) and protect from light to extend shelf life.
FAQs
1. Can Chlorodiisopropylphosphine be used directly in air-sensitive reactions?
While the AcroSeal® packaging reduces exposure, it is recommended to further purify or handle the reagent under inert gas (N₂/Ar) for air-sensitive applications. Degassing or distillation may be required for critical reactions.
2. What is the typical shelf life of this product when stored properly?
When stored unopened at 2-8°C in the original AcroSeal® bottle, the reagent retains ≥96% purity for 12–18 months. Opened bottles should be resealed under inert gas and used within 3–6 months.
3. Are there safer alternatives to Chlorodiisopropylphosphine for ligand synthesis?
Less volatile alternatives like dichlorophenylphosphine or solid-phase bound phosphines (e.g., polymer-supported PCl₃) can reduce handling risks, though they may alter reaction conditions or yields.
4. How should I dispose of unused or expired Chlorodiisopropylphosphine?
Neutralize with a compatible alcohol (e.g., ethanol) under fume hood conditions, then dispose as hazardous chemical waste according to local regulations. Avoid contact with water to prevent HCl gas formation.
5. Is this compound compatible with glassware, or should I use specific materials?
It is compatible with borosilicate glass, but prolonged storage may etch glass surfaces. For long-term storage, consider PTFE-lined containers or amber glass bottles to minimize degradation.
