Description
Specifications Table
Product Name – Isobutylmagnesium chloride, 2M solution in diethyl ether, AcroSeal®
Quantity/Pack Size – 100ML
Form – Liquid (solution in diethyl ether)
Grade – Reagent
Application – Grignard reagent for organic synthesis, alkylation, carbon-carbon bond formation
Product Overview
Isobutylmagnesium chloride (2M in diethyl ether) is a highly reactive Grignard reagent supplied in an air-tight AcroSeal® bottle to prevent moisture contamination and ensure long-term stability. This reagent-grade solution maintains a 99%+ assay purity, making it ideal for demanding organic synthesis applications where precise stoichiometry is critical. The anhydrous diethyl ether solvent enhances solubility while minimizing side reactions, and the sealed packaging eliminates the need for inert gas handling during storage. The 2M concentration provides an optimal balance between reactivity and ease of dosing, reducing solvent waste compared to more dilute alternatives. Each batch undergoes rigorous quality control to verify halogen content, solvent residual levels, and absence of peroxides. The solution’s low color index (<10 Hazen) indicates minimal oxidative degradation, while the hermetically sealed container prevents ether evaporation and atmospheric exposure. Compatible with standard Schlenk techniques, this product eliminates the hazards associated with preparing Grignard reagents in-house.
FAQs
1. What precautions should be taken when handling this 2M isobutylmagnesium chloride solution?
Always work under a fume hood with proper PPE, as the solution is pyrophoric and reacts violently with water. Use flame-dried glassware and maintain an inert atmosphere when transferring.
2. Can this reagent be used directly for coupling reactions without further purification?
The AcroSeal® packaging ensures high purity, but for moisture-sensitive applications, we recommend titrating the solution before use to confirm the exact molarity, as ether solvents may absorb trace water over time.
3. How does the AcroSeal® packaging differ from standard septum-sealed bottles?
AcroSeal® uses a patented valve system that creates a vacuum-sealed barrier, preventing solvent evaporation and atmospheric contamination more effectively than traditional septum caps, which can develop micro-leaks.
4. What is the typical shelf life of this product when stored unopened?
When stored at 2–8°C in the original unopened AcroSeal® bottle, the solution retains ≥98% of its labeled concentration for 12 months. Avoid freezing, as it may cause solvent separation.
5. Are there any known incompatibilities with common laboratory materials?
The solution corrodes aluminum and reacts with halogenated solvents (e.g., dichloromethane). Use only with borosilicate glass, PTFE, or stainless steel equipment, and avoid rubber stoppers, which may degrade.
