Description
Specifications Table
Product Name – Lithium diphenylphosphide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 100ML
Form – Liquid (solution in THF)
Grade – Reagent grade
Application – Organophosphorus synthesis, nucleophilic substitution
Product Overview
Lithium diphenylphosphide (0.5M in THF) is a highly reactive organolithium reagent designed for demanding synthetic applications. The solution is stabilized in anhydrous tetrahydrofuran (THF) under nitrogen atmosphere, ensuring minimal moisture exposure and prolonged shelf life. Packaged in an AcroSeal® bottle, this reagent maintains its integrity during storage and handling, making it suitable for sensitive reactions where precise stoichiometry is critical. The reagent grade purity guarantees consistent performance in nucleophilic substitutions, ligand formations, and other organophosphorus transformations. Its air-tight packaging prevents oxidation and degradation, while the standardized concentration simplifies dosing calculations. This solution is particularly valued for its ability to generate phosphine ligands in situ, eliminating the need for handling hazardous gaseous phosphines. The THF solvent is rigorously dried to meet strict anhydrous requirements, ensuring compatibility with moisture-sensitive reaction conditions.
FAQs
1. What is the typical shelf life of this lithium diphenylphosphide solution?
The solution remains stable for 12 months when stored unopened at room temperature in its original AcroSeal® packaging. After opening, use within 3 months for optimal reactivity.
2. Can this reagent be used with other solvents besides THF?
The solution is specifically formulated in THF for stability. Transferring to other solvents may cause precipitation or decomposition. For alternative solvent systems, consider preparing fresh solutions.
3. How should I dispose of unused lithium diphenylphosphide solution?
Neutralize with isopropanol or ethanol under inert atmosphere, then dilute with water before disposal. Follow local hazardous waste regulations for organolithium compounds.
4. Is this solution compatible with Schlenk line techniques?
Yes, the AcroSeal® bottle can be adapted to Schlenk lines using standard septa and cannula techniques. Ensure all glassware is thoroughly dried and purged with inert gas.
5. What alternatives exist for similar organophosphorus synthesis?
Sodium diphenylphosphide or potassium diphenylphosphide can be used, though they may require different reaction conditions. For solid reagents, consider diphenylphosphine with a separate base.
