Description
Specifications Table
Product Name – Lithium phenoxide, 0.6M solution in THF, AcroSeal®
Quantity/Pack Size – 100ML
Form – Liquid solution
Grade – Reagent grade
Application – Organic synthesis, nucleophilic substitution
Product Overview
Lithium phenoxide in THF (0.6M) is a highly reactive organolithium reagent solution designed for demanding organic synthesis applications. The AcroSeal® packaging ensures maximum stability by preventing moisture contamination, which is critical for maintaining reagent integrity during storage and handling. This solution offers consistent performance in nucleophilic substitution reactions, where precise stoichiometry and purity are essential. The anhydrous THF solvent provides an optimal medium for lithium phenoxide reactivity, while the standardized 0.6M concentration allows for accurate dosing without additional dilution steps. The reagent’s high purity minimizes side reactions, making it particularly suitable for sensitive synthetic pathways. Each batch undergoes rigorous quality control to ensure reproducible results in laboratory settings.
FAQs
1. What is the shelf life of this lithium phenoxide solution?
The unopened AcroSeal® bottle maintains stability for 24 months when stored at room temperature. After opening, use within 6 months for optimal performance.
2. Can this solution be used directly without further purification?
Yes, this reagent-grade solution is pre-purified and standardized to 0.6M concentration, ready for immediate use in synthesis protocols.
3. What precautions should be taken when handling this THF solution?
Work under inert atmosphere (nitrogen/argon) due to moisture sensitivity. Use standard THF handling precautions including proper ventilation and flame-resistant equipment.
4. How does the AcroSeal® packaging benefit this product?
The AcroSeal® technology provides an airtight barrier that prevents moisture ingress and solvent evaporation, preserving the reagent’s concentration and reactivity.
5. What alternatives exist for similar nucleophilic substitutions?
Sodium phenoxide or potassium phenoxide in DMSO could be considered, though reaction conditions and yields may differ significantly from lithium-based reagents.
