Specifications Table

Product Name – 2-Naphthylmagnesium bromide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 50ML
Form – Liquid (Solution in THF)
Grade – Reagent Grade
Application – Grignard reagent for organic synthesis

Product Overview

2-Naphthylmagnesium bromide is a highly reactive Grignard reagent supplied as a 0.5M solution in tetrahydrofuran (THF) under AcroSeal® packaging to prevent moisture contamination. This reagent is essential for carbon-carbon bond formation in organic synthesis, offering high nucleophilicity and selectivity. The THF solvent enhances solubility and reactivity, making it suitable for complex molecular constructions. The AcroSeal® technology ensures long-term stability by minimizing exposure to air and moisture, preserving reagent integrity. Ideal for researchers requiring precise control over reaction conditions, this solution maintains consistent performance across multiple applications. The reagent’s purity and concentration are optimized for reproducibility in laboratory settings, reducing variability in experimental outcomes. Store under inert atmosphere to prevent degradation and ensure optimal reactivity for critical synthesis steps.

FAQs

1. What is the shelf life of 2-Naphthylmagnesium bromide in THF?

The solution remains stable for 12 months when stored unopened under nitrogen at 2-8°C. Always check for turbidity before use.

2. Can this reagent be used directly without further purification?

Yes, the 0.5M solution is provided in reagent-grade purity and is ready for immediate use in synthesis.

3. Is this compatible with standard glassware?

Yes, but ensure all glassware is dry and inertized with nitrogen to prevent hydrolysis of the Grignard reagent.

4. What alternatives exist for similar naphthyl-based Grignard reagents?

1-Naphthylmagnesium bromide or naphthyl lithium reagents can be considered, though reactivity profiles differ.

5. How should I dispose of excess solution?

Neutralize with isopropanol or dilute acetic acid, then dispose as hazardous chemical waste according to local regulations.