Specifications Table
Product Name – ACETONITRILE 99.5% SPECIALLY DRIED
Quantity/Pack Size – 500 ml, 2500 ml
Form – Liquid
Grade – HPLC
Application – Chromatography, spectroscopy, solvent extraction
Product Overview
ACETONITRILE 99.5% SPECIALLY DRIED is a high-purity solvent engineered for demanding laboratory applications where minimal water content and exceptional clarity are critical. This grade is meticulously processed to ensure ultra-low moisture levels, making it ideal for high-performance liquid chromatography (HPLC), UV-Vis spectroscopy, and other analytical techniques requiring consistent baseline stability. Its high transparency in the UV range (down to 190 nm) ensures reliable detection of analytes, while its low reactivity and volatility provide precise solvent behavior in gradient elution systems. The specially dried formulation minimizes interference from residual water, enhancing peak resolution and reproducibility in chromatographic separations. Compatible with most organic and aqueous mobile phases, this acetonitrile variant is also widely used in sample preparation, protein purification, and as a reaction medium in organic synthesis. Its stability under standard lab conditions and resistance to microbial growth further extend its shelf life, ensuring long-term reliability for routine and high-throughput applications.
FAQs
1. Can this acetonitrile be used for LC-MS applications?
Yes, the 99.5% purity and low water content make it suitable for LC-MS, though additional filtering may be required for ultra-sensitive mass spectrometry to prevent ion suppression.
2. What is the typical water content in this specially dried grade?
The water content is maintained below 0.01% (100 ppm), significantly lower than standard HPLC-grade acetonitrile, ensuring minimal interference in moisture-sensitive reactions.
3. Is this compatible with reverse-phase HPLC columns?
Yes, it is fully compatible with C18, C8, and other reverse-phase columns, though column equilibration with the mobile phase is recommended before use.
4. How should this solvent be stored to maintain purity?
Store in a tightly sealed glass bottle under nitrogen or argon blanket if possible, away from direct sunlight and moisture, at room temperature (15–25°C). Avoid prolonged exposure to air.
5. What alternatives exist if this grade is unavailable?
For general HPLC, standard HPLC-grade acetonitrile (99.9%) can be used, but for moisture-sensitive applications, molecular sieves (3Ã…) can be added to standard grades to reduce water content.
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