Description
Specifications Table
Product Name – N,O-BIS(TRIMETHYLSILYL) ACETAMIDE 95% For Synthesis
Quantity/Pack Size – 25 ml, 100 ml, 500 ml
Form – Liquid
Grade – For Synthesis
Application – Silylation reagent for GC-MS, HPLC, and NMR sample preparation
Product Overview
N,O-Bis(trimethylsilyl)acetamide (BSA) 95% is a high-purity silylating reagent designed for laboratory applications requiring efficient derivatization of polar functional groups. This reagent is particularly valued for its ability to convert active hydrogen-containing compounds into volatile trimethylsilyl (TMS) derivatives, enhancing their compatibility with chromatographic techniques such as gas chromatography-mass spectrometry (GC-MS) and high-performance liquid chromatography (HPLC). The 95% purity ensures minimal interference from impurities, making it ideal for sensitive analytical procedures. BSA exhibits low moisture sensitivity compared to other silylating agents, providing greater stability during storage and handling. Its liquid form allows for easy dispensing and precise volume control, which is critical for reproducible results in quantitative analysis. The reagent is compatible with a wide range of organic solvents, enabling seamless integration into existing laboratory protocols. Whether used for small-scale research or routine sample preparation, this BSA grade delivers consistent performance, reducing the need for repeated derivatization steps and improving overall workflow efficiency.
FAQs
1. What is the primary function of N,O-Bis(trimethylsilyl)acetamide in laboratory applications?
It acts as a silylating agent, converting polar functional groups into trimethylsilyl derivatives to improve volatility and stability for chromatographic analysis.
2. How should this reagent be stored to maintain its stability?
Store in a tightly sealed container under inert gas, preferably in a cool, dry place away from moisture and direct sunlight.
3. Is this BSA grade compatible with automated sample preparation systems?
Yes, its liquid form and consistent purity make it suitable for automated liquid handling systems used in high-throughput laboratories.
4. What precautions should be taken when handling this reagent?
Use in a fume hood with proper ventilation, wear protective gloves and eyewear, and avoid exposure to moisture to prevent premature hydrolysis.
5. Can this reagent be used for both qualitative and quantitative analysis?
Yes, its high purity and reproducible derivatization make it suitable for both qualitative identification and quantitative determination of analytes.










