Description
Specifications Table
Product Name – N,N-Dimethylformamide, 99.8%, Extra Dry over Molecular Sieve, AcroSeal®
Quantity/Pack Size – 100ML, 500ML, 1LT, 2.5LT
Form – Liquid
Grade – Extra Dry (99.8% purity)
Application – Solvent for organic synthesis, peptide coupling, and moisture-sensitive reactions
Product Overview
N,N-Dimethylformamide (DMF) 99.8% Extra Dry is a high-purity, anhydrous solvent specifically processed over molecular sieves to achieve ultra-low water content (<50 ppm), making it ideal for moisture-sensitive chemical reactions. The AcroSeal® packaging system provides an additional barrier against atmospheric moisture and contaminants, ensuring consistent performance in critical applications. This grade of DMF is particularly valued in organic synthesis, peptide chemistry, and polymerization processes where trace water can compromise yields or reaction selectivity. The solvent's high polarity and aprotic nature enable excellent solvation of both polar and nonpolar compounds, while its thermal stability allows for use in reactions requiring elevated temperatures. The extra dry specification minimizes side reactions like hydrolysis or transesterification that could occur with standard-grade DMF. Each batch undergoes rigorous quality control to verify the absence of impurities such as dimethylamine or formic acid, which could interfere with sensitive analytical techniques or catalytic systems.
FAQs
1. What makes this DMF “extra dry” compared to standard grades?
The extra dry designation indicates this DMF has been subjected to molecular sieve treatment to reduce water content to below 50 ppm, compared to standard grades which may contain 100-300 ppm water. This ultra-low moisture level is critical for reactions like Grignard formations or lithium-aluminum hydride reductions where trace water would terminate the reaction.
2. Can this DMF be used directly from the bottle without further drying?
Yes, the AcroSeal® packaging and molecular sieve drying process ensure the solvent meets the extra dry specification upon opening. However, for extremely moisture-sensitive applications, some researchers may choose to perform additional drying with activated molecular sieves (3Å or 4Å) as a precautionary measure.
3. What is the typical shelf life of this extra dry DMF?
When stored unopened in its original AcroSeal® container at room temperature, this DMF maintains its extra dry specification for at least 24 months from the date of manufacture. Once opened, the shelf life depends on storage conditions and frequency of use, but the molecular sieve cap helps preserve dryness during short-term storage.
4. Is this DMF compatible with all common laboratory plastics?
DMF is known to dissolve or swell many plastics including polystyrene, polycarbonate, and some grades of polyethylene. For storage and handling, use glass containers or HDPE bottles specifically rated for DMF. The AcroSeal® bottle is constructed from materials compatible with DMF to prevent leaching or container degradation.
5. How does the AcroSeal® packaging differ from standard solvent bottles?
The AcroSeal® system incorporates a specialized septum and cap design that creates a moisture barrier, along with an integrated molecular sieve in the cap to absorb any atmospheric moisture during storage. This design significantly reduces the risk of water contamination compared to traditional screw-cap bottles, particularly in humid laboratory environments.
