Description
Specifications Table
Product Name – Lithium diisopropylamide, 2M sol. in THF/n-heptane/ethylbenzene, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid (Solution)
Grade – Reagent Grade
Application – Strong non-nucleophilic base for organic synthesis
Product Overview
Lithium diisopropylamide (LDA) is a highly reactive, non-nucleophilic strong base widely used in organic synthesis for selective deprotonation reactions. This 2M solution in THF/n-heptane/ethylbenzene provides consistent performance with enhanced stability due to the AcroSeal® packaging, which minimizes moisture and air exposure. The reagent-grade quality ensures high purity, making it suitable for demanding laboratory applications where precise control over reaction conditions is critical. The solvent blend optimizes solubility and reactivity while maintaining safety during handling. LDA’s steric bulk prevents nucleophilic side reactions, allowing for clean enolate formation in carbonyl chemistry. Its compatibility with low-temperature conditions further expands its utility in sensitive transformations. The sealed packaging preserves potency over extended storage periods, reducing waste and ensuring reliable results across multiple experiments.
FAQs
1. What is the typical shelf life of this LDA solution?
The AcroSeal® packaging extends shelf life to 12-18 months when stored properly at 2-8°C, though potency should be verified before critical applications.
2. Can this LDA solution be used for kinetic enolate formation?
Yes, the 2M concentration and solvent system are specifically optimized for kinetic deprotonation reactions at low temperatures.
3. What precautions should be taken when handling this solution?
Always use in a well-ventilated fume hood with proper PPE, as the solution is highly flammable and reacts violently with water.
4. Is this LDA solution compatible with glass reaction vessels?
The solution is fully compatible with standard borosilicate glassware, though PTFE-coated stir bars are recommended for sensitive applications.
5. How does the n-heptane/ethylbenzene blend affect reactivity?
The hydrocarbon cosolvents moderate the basicity while improving solubility of organic substrates compared to pure THF solutions.
