Description
Specifications Table
Product Name – Lithium tert-butoxide, 0.9M (8 wt.%) solution in 2-MeTHF, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Solution
Grade – Laboratory Grade
Application – Organic synthesis, deprotonation reactions
Product Overview
Lithium tert-butoxide, 0.9M (8 wt.%) solution in 2-MeTHF, is a highly reactive, non-nucleophilic base widely used in organic synthesis. The solution is stabilized in 2-methyltetrahydrofuran (2-MeTHF), a solvent known for its compatibility with a broad range of reactions. This formulation ensures high solubility and reactivity, making it ideal for deprotonation reactions, enolate formation, and other base-catalyzed transformations. The AcroSeal® packaging guarantees minimal exposure to moisture and air, preserving the reagent’s potency and extending shelf life. The solution is provided in laboratory-grade purity, ensuring consistent and reliable results in research and development applications. Its strong basicity and steric hindrance make it particularly effective in selective deprotonation without nucleophilic side reactions. The 2-MeTHF solvent further enhances its utility by offering a wider liquid range and better stability compared to traditional solvents like THF.
FAQs
1. What is the shelf life of Lithium tert-butoxide solution in 2-MeTHF?
The shelf life is typically 12-24 months when stored under recommended conditions in its original AcroSeal® packaging.
2. Is this solution compatible with glassware?
Yes, it is compatible with standard borosilicate glassware, but prolonged exposure should be avoided to prevent etching.
3. Can this solution be used as a substitute for LDA?
In many cases, yes, as it offers similar strong basicity but with different selectivity and solubility profiles.
4. How should this solution be stored?
Store in a cool, dry place under an inert atmosphere, away from moisture and ignition sources.
5. What precautions should be taken while handling?
Use in a fume hood with proper PPE, as it is highly flammable and corrosive. Avoid contact with skin and eyes.
