Description
Specifications Table
Product Name – Octylmagnesium bromide, 2M solution in diethyl ether, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid (solution in diethyl ether)
Grade – AcroSeal® (high purity)
Application – Grignard reagent for organic synthesis
Product Overview
Octylmagnesium bromide, 2M solution in diethyl ether (AcroSeal®), is a highly reactive Grignard reagent designed for precision in organic synthesis. The 2M concentration ensures optimal reactivity while the diethyl ether solvent stabilizes the organomagnesium compound. Packaged under nitrogen in AcroSeal® bottles, this solution maintains purity by preventing air and moisture contamination, which is critical for reproducible results. The octyl group provides unique reactivity profiles compared to shorter-chain Grignard reagents, making it ideal for specialized carbon-carbon bond formations. The solution appears as a clear to pale yellow liquid, though slight turbidity may occur due to the reagent’s sensitivity. Each batch undergoes rigorous quality control to ensure consistent molar concentration and minimal impurities. The AcroSeal® packaging features a tamper-evident seal and is compatible with standard Schlenk techniques for safe handling. This product is particularly valued in research settings where high-purity organometallic reagents are essential for complex synthetic pathways.
FAQs
1. What precautions should be taken when handling this Grignard reagent?
Always work under inert atmosphere using Schlenk techniques or glove boxes. The solution is highly flammable and reacts violently with water, releasing hydrogen gas. Use dry glassware and solvents to prevent decomposition.
2. Can this solution be used with other solvents besides diethyl ether?
The reagent is specifically stabilized in diethyl ether. Transferring to other solvents may cause precipitation or altered reactivity. If solvent exchange is necessary, perform under strict anhydrous conditions with compatibility testing.
3. How should this product be stored for maximum shelf life?
Store unopened bottles at 2-8°C in a dedicated flammable liquids cabinet. Once opened, use immediately or store under nitrogen with minimal headspace. Avoid temperature fluctuations which can cause ether evaporation and concentration changes.
4. What is the typical reaction yield when using this reagent?
Yields typically range from 70-95% depending on the specific reaction conditions and substrate purity. The 2M concentration provides a good balance between reactivity and handling ease, though optimization may be required for sterically hindered substrates.
5. Are there any known impurities that might affect reactions?
The primary potential impurities are magnesium bromide and trace amounts of octane from decomposition. The AcroSeal® packaging minimizes these, but fresh solutions generally perform better in sensitive applications. Always verify concentration via titration if critical.
