Description
Specifications Table
| Product Name | 1-Hexanesulfonic acid sodium salt, anhydrous HPLC |
|---|---|
| Quantity/Pack Size | 25 g |
| Form | Powder |
| Grade | HPLC |
| Application | Ion pair reagent for HPLC, chromatographic analysis |
Product Description
When precision matters in HPLC analysis, 1-hexanesulfonic acid sodium salt stands out as a trusted ion pair reagent. This anhydrous, HPLC-grade chemical is designed to enhance separation efficiency in reverse-phase chromatography, making it indispensable for labs analyzing complex mixtures.
Whether you’re a student fine-tuning a research project or a seasoned chemist validating methods, this reagent ensures sharp, reproducible peaks. Its high purity minimizes interference, while the anhydrous form guarantees stability in storage. For researchers working with polar compounds, this sodium salt acts as a counterion, improving retention and resolution.
Why settle for less when eqipped delivers lab-grade reliability? Each 25 g pack is rigorously tested to meet HPLC standards, so you can focus on your experiments without worrying about reagent quality.
From pharmaceutical assays to environmental testing, this versatile reagent adapts to diverse applications. Its solubility in water and organic solvents adds flexibility to your workflow. And because it’s sourced from Avantor, you’re getting a product backed by decades of expertise in analytical chemistry.
Upgrade your HPLC separations today—order 1-hexanesulfonic acid sodium salt from eqipped.
How to Use 1-Hexanesulfonic Acid Sodium Salt in HPLC
Using this reagent effectively requires careful optimization. Start by preparing a stock solution (typically 0.01-0.1 M) in your mobile phase. The concentration depends on your analyte’s polarity—higher concentrations improve retention for strongly polar compounds.
Always filter your mobile phase through a 0.45 µm membrane to prevent column clogging. For gradient methods, ensure the ion pair reagent is present in both solvents to maintain consistent ionization. Remember, pH adjustments may be necessary to optimize peak shape.
Pro tip: If you notice peak tailing, try reducing the reagent concentration or adjusting the pH. For best results, store solutions at room temperature and use within a week to prevent microbial growth.
Safety and Handling
While 1-hexanesulfonic acid sodium salt is generally safe when handled properly, always follow standard lab practices. Wear nitrile gloves and safety goggles when weighing or preparing solutions. Avoid inhalation of dust and work in a well-ventilated area.
In case of skin contact, rinse immediately with plenty of water. For accidental ingestion, seek medical attention. Dispose of waste solutions according to local regulations for organic sulfonic acids.
FAQs
What is the shelf life of 1-hexanesulfonic acid sodium salt?
When stored in a cool, dry place in its original container, this reagent remains stable for at least 2 years. Always check for signs of moisture absorption before use.
Can I use this reagent for LC-MS applications?
While effective for HPLC-UV, this non-volatile ion pair reagent isn’t suitable for LC-MS. For mass spec applications, consider volatile alternatives like trifluoroacetic acid.
How does this compare to other ion pair reagents?
Sodium 1-hexanesulfonate offers a balance between hydrophobicity and solubility. It’s less aggressive than longer-chain reagents but more effective than butanesulfonate for moderately polar compounds.
What’s the typical concentration range for mobile phases?
Most applications use 5-20 mM concentrations. Start with 10 mM and adjust based on your analyte’s retention behavior.
Is this product compatible with all HPLC columns?
It works well with C18 and C8 columns. However, avoid using it with columns sensitive to ion pair reagents, such as some HILIC phases.
