Description
Specifications Table
Product Name – 1-Octanesulfonic acid sodium salt, anhydrous HPLC
Quantity/Pack Size – 25 g
Form – Solid (powder/crystals)
Grade – HPLC
Application – Ion-pair chromatography, reverse-phase HPLC
Product Overview
1-Octanesulfonic acid sodium salt, anhydrous, is a high-purity ion-pairing reagent specifically designed for HPLC applications. This compound is widely recognized for its ability to improve chromatographic separation of polar and ionic analytes, particularly in reverse-phase HPLC systems. The anhydrous form ensures minimal moisture content, which is critical for maintaining consistent retention times and peak shapes. With its low UV absorbance, it minimizes interference in UV detection, making it ideal for sensitive analytical methods. The salt exhibits excellent solubility in aqueous and organic solvents, allowing for flexible mobile phase preparation. Its chemical stability under typical HPLC conditions ensures reliable and reproducible results across multiple runs. The product is rigorously tested to meet HPLC-grade standards, guaranteeing high purity and minimal impurities that could affect chromatographic performance. Whether used in isocratic or gradient elution, this reagent provides robust ion-pairing capabilities, enhancing the resolution of complex mixtures. The 25 g pack size offers convenience for laboratories with moderate to high usage requirements, reducing the need for frequent reordering while maintaining freshness.
FAQs
1. What is the primary function of 1-octanesulfonic acid sodium salt in HPLC?
It acts as an ion-pairing reagent that improves the separation of polar and ionic compounds in reverse-phase HPLC by forming neutral ion pairs with charged analytes.
2. Is this product compatible with mass spectrometry (MS) detection?
While it can be used with MS, its non-volatile nature may require additional optimization or alternative reagents to prevent ion suppression or source contamination.
3. What are the recommended storage conditions for this product?
Store in a cool, dry place away from moisture and direct sunlight. Keep the container tightly sealed to prevent hydration and degradation.
4. Can this be used as a substitute for heptanesulfonic acid sodium salt?
Yes, but retention times may vary due to differences in alkyl chain length. Method reoptimization is recommended when switching between ion-pairing reagents.
5. What solvents are typically used to prepare mobile phases with this reagent?
It is commonly dissolved in water or methanol, often combined with acetonitrile or other organic modifiers depending on the specific HPLC method requirements.
