Description
Specifications Table
Product Name – 1-Octanesulfonic acid, sodium salt HPLC
Quantity/Pack Size – 25 g
Form – Solid
Grade – HPLC
Application – Ion-pair chromatography, analytical separations
Product Overview
1-Octanesulfonic acid sodium salt HPLC is a high-purity ion-pairing reagent designed for precise chromatographic separations. This sodium salt form enhances solubility in aqueous mobile phases, making it ideal for reverse-phase HPLC applications where retention and selectivity of ionic or polar compounds are critical. Its long hydrophobic alkyl chain (C8) ensures strong interaction with analytes, improving peak shape and resolution. The HPLC-grade purity minimizes interference, ensuring reliable and reproducible results in complex sample matrices. This reagent is particularly effective for separating organic acids, bases, and other ionizable compounds, offering consistent performance across a wide pH range. The solid form allows for easy handling and accurate weighing, while its stability under standard lab conditions ensures long shelf life without degradation. Whether used in isocratic or gradient elution, this reagent maintains robust retention characteristics, making it a versatile choice for demanding analytical workflows.
FAQs
1. What is the primary function of 1-Octanesulfonic acid sodium salt in HPLC?
It acts as an ion-pairing reagent to improve the separation of ionic or polar compounds in reverse-phase HPLC by forming neutral ion pairs that interact more strongly with the stationary phase.
2. Is this reagent compatible with mass spectrometry (LC-MS) applications?
While it can be used, its non-volatile nature may cause ion suppression or source contamination. For LC-MS, volatile ion-pairing reagents like trifluoroacetic acid are generally preferred.
3. How should this product be stored to maintain its stability?
Store in a tightly sealed container at room temperature, protected from moisture and light. Avoid exposure to extreme temperatures or humidity to prevent degradation.
4. Can this be used as an alternative to hexanesulfonic acid sodium salt?
Yes, but with adjusted retention times due to the longer C8 chain, which provides stronger hydrophobic interactions compared to the C6 chain in hexanesulfonic acid.
5. What is the typical concentration range used in mobile phases?
Concentrations typically range from 1 to 10 mM, depending on the analyte and desired retention. Higher concentrations increase retention but may require optimization for peak symmetry.
