Specifications Table

Product Name – 1,4-Dioxane 99.5% AR
Quantity/Pack Size – 500 ml, 2500 ml
Form – Liquid
Grade – AR (Analytical Reagent)
Application – Solvent for organic synthesis, HPLC, GC, and extraction processes

Product Overview

1,4-Dioxane 99.5% AR is a high-purity, water-miscible cyclic ether widely used as a solvent in laboratory applications. This analytical reagent (AR) grade variant ensures minimal impurities, making it suitable for critical processes such as chromatography, organic synthesis, and sample preparation. The solvent exhibits excellent stability and low reactivity, preserving the integrity of sensitive compounds during reactions. Its hygroscopic nature demands proper storage to maintain purity, while its broad solubility profile allows seamless integration into diverse experimental protocols. The 99.5% purity level guarantees consistent performance in GC, HPLC, and spectroscopic analyses, where trace contaminants could compromise results. As a versatile aprotic solvent, it effectively dissolves both polar and nonpolar substances, facilitating homogeneous reaction mixtures. The AR grade designation confirms adherence to stringent quality standards, ensuring reproducibility in research and industrial applications.

FAQs

1. What is the shelf life of 1,4-Dioxane 99.5% AR when stored properly?

When stored in a tightly sealed container away from moisture and direct sunlight, 1,4-Dioxane 99.5% AR maintains its specified purity for up to 24 months from the date of manufacture. Regularly check for peroxide formation if stored beyond this period.

2. Can this grade of 1,4-Dioxane be used for peroxide-sensitive reactions?

While 1,4-Dioxane itself doesn’t readily form peroxides, this AR grade is stabilized to minimize peroxide contamination. For highly peroxide-sensitive applications, we recommend testing with peroxide test strips before use or opting for peroxide-free certified variants.

3. How does the purity of this solvent compare to HPLC-grade 1,4-Dioxane?

This 99.5% AR grade contains slightly higher permissible impurities compared to HPLC-grade (typically ≥99.9%). The AR grade is suitable for most general lab applications, while HPLC-grade would be preferred for ultra-sensitive chromatographic analyses where baseline noise must be minimized.

4. What precautions should be taken when handling 1,4-Dioxane in the lab?

Always handle in a well-ventilated fume hood as 1,4-Dioxane vapors are harmful. Use chemical-resistant gloves (nitrile or neoprene) and safety goggles. Avoid inhalation and skin contact, as it’s classified as a potential carcinogen. Work with small quantities to minimize exposure risks.

5. Is this solvent compatible with standard borosilicate glass containers?

Yes, 1,4-Dioxane can be safely stored in borosilicate glass containers. However, for long-term storage, we recommend using containers with PTFE-lined caps to prevent moisture absorption and potential leaching from rubber liners.