Description
Specifications Table
Product Name – 17-AAG (17-Allylamino-17-Demethoxygeldanamycin)
Quantity/Pack Size – 1 mg
Form – Powder
Grade – Analytical
Application – Lab Research
Product Overview
17-AAG (17-Allylamino-17-Demethoxygeldanamycin) is a semi-synthetic analog of geldanamycin, a benzoquinone ansamycin antibiotic. It is known for its ability to inhibit the heat shock protein 90 (Hsp90), which plays a crucial role in the folding and stabilization of various client proteins, including several oncoproteins. This makes 17-AAG a valuable tool in cancer research, particularly in studies focusing on the inhibition of Hsp90 and its downstream effects on cellular processes. The compound is supplied in a high-purity form, ensuring reliable and reproducible results in laboratory experiments. Its analytical grade makes it suitable for a wide range of research applications, from in vitro studies to more complex biological assays.
FAQs
1. What is the primary application of 17-AAG (17-Allylamino-17-Demethoxygeldanamycin)?
17-AAG is primarily used in cancer research to inhibit the heat shock protein 90 (Hsp90).
2. Is 17-AAG compatible with all lab equipment?
17-AAG is compatible with standard lab equipment used for handling and analyzing chemical compounds.
3. Are there any alternatives to 17-AAG for Hsp90 inhibition?
Yes, there are other Hsp90 inhibitors available, such as geldanamycin and radicicol, but 17-AAG is one of the most studied.
4. How should 17-AAG be stored?
17-AAG should be stored at -20°C in a tightly sealed container to maintain its stability and purity.
5. Where is 17-AAG sourced from?
17-AAG is sourced from reputable chemical suppliers who specialize in high-purity lab reagents.
