Description

Specifications Table

Product Name – 1,8-Diazabicyclo(5.4.0)undec-7-ene (DBU) Quantity/Pack Size – 100 ml Form – Liquid Grade – ≥99% purity Application – Superbase catalyst, organic synthesis

Product Overview

1,8-Diazabicyclo(5.4.0)undec-7-ene (DBU) is an exceptionally strong organic superbase widely recognized for its catalytic properties in organic synthesis. This high-purity (≥99%) reagent features a unique bicyclic structure that provides both steric hindrance and powerful basicity, making it indispensable for demanding chemical transformations. The colorless liquid form ensures easy handling and precise dosing in laboratory applications. DBU’s non-nucleophilic nature allows it to deprotonate weak acids without participating in side reactions, while its high boiling point (256-258°C) enables reactions at elevated temperatures. The reagent’s stability under various conditions and compatibility with diverse solvents expands its utility across multiple synthetic pathways. Its low volatility reduces exposure risks during handling, while the concentrated form (100ml packaging) provides cost-effective usage for both small-scale and bulk applications. The product’s consistent quality and reliable performance make it a preferred choice for researchers requiring reproducible results in complex organic transformations.

FAQs

1

What is the exact pKa value of DBU?

DBU has an approximate pKa value of 13.6, which contributes to its classification as a superbase. This high basicity enables it to deprotonate a wide range of acidic compounds that weaker bases cannot.

2

Can DBU be used with aqueous reaction systems?

While DBU is soluble in organic solvents, its use in purely aqueous systems is limited due to hydrolysis potential. For aqueous-organic mixed systems, careful pH monitoring is recommended to maintain reaction integrity.

3

What are the primary safety considerations when handling DBU?

The main safety concerns include its corrosive nature and potential skin/eye irritation. Always use in a fume hood with proper PPE including nitrile gloves and safety goggles. The reagent should be stored away from acids and oxidizing agents.

4

How does DBU compare to other superbases like TMG or BEMP?

DBU offers a balance between basicity and steric bulk that differs from tetramethylguanidine (TMG) or 2-tert-butylimino-2-diethylamino-1,3-dimethylperhydro-1,3,2-diazaphosphorine (BEMP). It provides stronger basicity than TMG but with less steric hindrance than BEMP, making it versatile for various applications.

5

What is the typical shelf life of DBU when stored properly?

When stored in its original tightly sealed container at room temperature, protected from moisture and light, DBU maintains its specified purity for at least 24 months from the date of manufacture.