Specifications Table

Product Name – 2-Bromo-3′-methoxyacetophenone
Quantity/Pack Size – 10GR
Form – Solid (Powder/Crystals)
Grade – 97%
Application – Organic synthesis, intermediate in pharmaceutical and agrochemical research

Product Overview

2-Bromo-3′-methoxyacetophenone is a high-purity aromatic ketone (97% assay) widely used as a key intermediate in organic synthesis. This brominated acetophenone derivative features a methoxy substitution at the 3′ position, enhancing its reactivity for nucleophilic substitutions, cross-coupling reactions, and further functional group transformations. The compound’s crystalline solid form ensures stability during storage and handling, while its verified purity minimizes side reactions, making it ideal for demanding laboratory applications. The presence of both bromine and methoxy groups allows for selective modifications, enabling the synthesis of complex molecular structures. Its consistent batch-to-batch quality ensures reproducible results in research settings. The chemical is packaged under inert conditions to prevent moisture absorption, preserving its integrity for long-term use. Compatible with common organic solvents, it dissolves readily for homogeneous reactions, though proper ventilation and protective equipment are recommended during handling due to its potential irritant properties.

FAQs

1. What is the exact purity level of this 2-Bromo-3′-methoxyacetophenone?

The product is certified at 97% purity, verified through analytical techniques such as HPLC or GC to ensure minimal impurities for reliable synthesis outcomes.

2. Can this compound be used directly in Suzuki-Miyaura coupling reactions?

Yes, the bromine substituent makes it suitable for Suzuki-Miyaura cross-coupling, though optimization of catalysts and conditions may be required based on the specific reaction partners.

3. How should this chemical be stored to maintain its stability?

Store in a tightly sealed container under cool, dry conditions (2–8°C), protected from light and moisture. Avoid prolonged exposure to air to prevent oxidation or hydrolysis.

4. Is this product compatible with polar aprotic solvents like DMF or DMSO?

It dissolves well in polar aprotic solvents, but solubility should be tested for specific concentrations, as high loads may require gentle heating or sonication.

5. Are there safer alternatives for similar synthesis applications?

Alternatives like 2-chloro-3′-methoxyacetophenone may offer milder reactivity, but the bromo derivative is often preferred for its higher yield in cross-coupling reactions. Always assess hazard profiles before substitution.