Specifications Table

Product Name – 2-Methyl-2-phenylpropylmagnesium chloride, 0.5M solution in diethyl ether, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid (solution in diethyl ether)
Grade – Laboratory grade
Application – Organic synthesis, Grignard reactions

Product Overview

This 0.5M 2-Methyl-2-phenylpropylmagnesium chloride solution in diethyl ether is a specialized Grignard reagent designed for precise organic synthesis applications. The AcroSeal® packaging ensures air-tight protection, maintaining reagent purity and reactivity by preventing moisture contamination. The solution is stabilized in anhydrous diethyl ether, providing consistent performance in carbon-carbon bond formation reactions. The reagent’s structure features a bulky tertiary alkyl group adjacent to the magnesium center, which can influence reaction selectivity and stereochemistry. The 0.5M concentration offers an optimal balance between reactivity and handling convenience, allowing for accurate stoichiometric control in synthetic procedures. The solution is provided in amber glass bottles to protect against light-induced decomposition, with each bottle equipped with a secure septum cap for safe dispensing and storage.

FAQs

1. What precautions should be taken when handling this Grignard reagent?

Always work under inert atmosphere (nitrogen/argon) and use flame-dried glassware. The ether solvent is highly flammable, so avoid open flames and static discharge.

2. Can this reagent be used for preparing sterically hindered ketones?

The bulky tertiary alkyl structure makes it particularly suitable for reactions where steric hindrance might be beneficial for selectivity.

3. How should the unopened bottles be stored for long-term use?

Store upright in a cool, dry place away from direct sunlight. The AcroSeal® packaging maintains integrity for extended periods when unopened.

4. What is the typical shelf life of this solution when stored properly?

When stored unopened in its original packaging at recommended conditions, the reagent maintains its specified concentration for at least 12 months.

5. Are there any special disposal requirements for this chemical?

The reagent should be quenched with isopropanol or saturated ammonium chloride solution before disposal according to local hazardous waste regulations.