Specifications Table

Product Name – [3-(4-Morpholinylmethyl)phenyl]magnesium bromide, 0.25M solution in THF, AcroSeal®
Quantity/Pack Size – 50ML
Form – Liquid (Solution in THF)
Grade – Reagent Grade
Application – Organic synthesis, Grignard reactions

Product Overview

[3-(4-Morpholinylmethyl)phenyl]magnesium bromide is a 0.25M Grignard reagent solution in tetrahydrofuran (THF), packaged under AcroSeal® technology to ensure moisture-free stability and extended shelf life. This reagent-grade solution is specifically designed for high-efficiency organic synthesis, offering consistent reactivity in carbon-carbon bond formation and nucleophilic addition reactions. The THF solvent provides optimal solubility and reaction kinetics, while the AcroSeal® packaging prevents degradation from atmospheric moisture or oxygen exposure. The morpholinylmethyl functional group introduces unique reactivity profiles, making this reagent particularly valuable for synthesizing complex organic molecules with precise structural control. Its standardized 0.25M concentration allows for accurate stoichiometric calculations in laboratory protocols. The solution maintains stability under recommended storage conditions, ensuring reliable performance across multiple experimental batches.

FAQs

1

What is the typical shelf life of this Grignard reagent solution?

The AcroSeal® packaging extends shelf life to 12-18 months when stored at 2-8°C, though reactivity should be verified before critical applications. 2

Can this reagent be used directly without further purification?

The reagent grade quality typically allows direct use, but filtration through activated alumina may be advisable for moisture-sensitive applications. 3

What safety precautions are essential when handling this THF solution?

Standard Grignard handling protocols apply: use in a fume hood, avoid water contact, and employ flame-resistant equipment due to THF’s flammability. 4

How does the morpholinylmethyl group affect reactivity compared to simpler Grignard reagents?

The electron-donating morpholine moiety enhances nucleophilicity while providing steric bulk that can influence regioselectivity in certain reactions. 5

What’s the recommended storage temperature for maintaining optimal reactivity?

Store at 2-8°C in the original sealed container, protected from light and moisture for maximum stability.