3,4-Dimethylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal® 50ML

Thermo Fisher Scientific Chemicals Dealer | eqipped

3,4-Dimethylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal® 50ML

High-purity 3,4-Dimethylphenylmagnesium bromide 0.5M THF solution, AcroSeal®-packed for moisture-sensitive Grignard synthesis and organometallic applications.

Original price was: ₹28,003.00.Current price is: ₹19,602.00.

Specifications Table

Product Name – 3,4-Dimethylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 50ML
Form – Solution
Grade – Reagent
Application – Grignard reagent, organometallic synthesis, aryl coupling

Product Overview

3,4-Dimethylphenylmagnesium bromide is a specialized Grignard reagent supplied as a 0.5M solution in anhydrous tetrahydrofuran (THF) under the AcroSeal® packaging system, ensuring maximum stability and moisture protection. This organomagnesium compound features a dimethyl-substituted phenyl ring, offering enhanced reactivity in carbon-carbon bond formation compared to unsubstituted analogs. The THF solvent provides optimal solubility for nucleophilic addition and substitution reactions, while the sealed packaging prevents degradation from atmospheric exposure. The reagent is particularly valued for its ability to introduce the 3,4-dimethylphenyl moiety into target molecules with high regioselectivity. The 0.5M concentration balances reactivity with ease of handling, making it suitable for both small-scale and preparative applications. As a moisture-sensitive compound, it requires inert atmosphere handling and storage at recommended temperatures to maintain its reactivity profile. The AcroSeal® system’s tamper-evident design ensures product integrity from manufacture to use, while the amber glass bottle provides additional protection against light-induced decomposition.

FAQs

1. What is the typical shelf life of 3,4-Dimethylphenylmagnesium bromide solution?

The solution maintains optimal reactivity for 12 months when stored unopened at 2-8°C under inert atmosphere conditions. Once opened, use within 3 months.

2. Can this reagent be used with other solvents besides THF?

While formulated in THF for stability, it can be transferred to anhydrous diethyl ether or toluene under inert conditions, though reactivity profiles may vary.

3. What are the key safety precautions for handling this solution?

Always handle under nitrogen or argon atmosphere using flame-dried glassware. The solution is highly flammable and reacts violently with water.

4. How does the dimethyl substitution affect reactivity compared to phenylmagnesium bromide?

The electron-donating methyl groups increase nucleophilicity at the ortho/para positions, often resulting in faster reaction rates in electrophilic aromatic substitutions.

5. What’s the recommended procedure for transferring the solution?

Use a dry, inert-gas purged syringe with PTFE plunger or cannula transfer technique under positive nitrogen pressure to prevent moisture contamination.

Thermo Fisher Scientific Chemicals Dealer | eqipped

3,4-Dimethylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal® 50ML

Original price was: ₹28,003.00.Current price is: ₹19,602.00.

High-purity 3,4-Dimethylphenylmagnesium bromide 0.5M THF solution, AcroSeal®-packed for moisture-sensitive Grignard synthesis and organometallic applications.

Specifications Table

Product Name – 3,4-Dimethylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 50ML
Form – Solution
Grade – Reagent
Application – Grignard reagent, organometallic synthesis, aryl coupling

Product Overview

3,4-Dimethylphenylmagnesium bromide is a specialized Grignard reagent supplied as a 0.5M solution in anhydrous tetrahydrofuran (THF) under the AcroSeal® packaging system, ensuring maximum stability and moisture protection. This organomagnesium compound features a dimethyl-substituted phenyl ring, offering enhanced reactivity in carbon-carbon bond formation compared to unsubstituted analogs. The THF solvent provides optimal solubility for nucleophilic addition and substitution reactions, while the sealed packaging prevents degradation from atmospheric exposure. The reagent is particularly valued for its ability to introduce the 3,4-dimethylphenyl moiety into target molecules with high regioselectivity. The 0.5M concentration balances reactivity with ease of handling, making it suitable for both small-scale and preparative applications. As a moisture-sensitive compound, it requires inert atmosphere handling and storage at recommended temperatures to maintain its reactivity profile. The AcroSeal® system’s tamper-evident design ensures product integrity from manufacture to use, while the amber glass bottle provides additional protection against light-induced decomposition.

FAQs

1. What is the typical shelf life of 3,4-Dimethylphenylmagnesium bromide solution?

The solution maintains optimal reactivity for 12 months when stored unopened at 2-8°C under inert atmosphere conditions. Once opened, use within 3 months.

2. Can this reagent be used with other solvents besides THF?

While formulated in THF for stability, it can be transferred to anhydrous diethyl ether or toluene under inert conditions, though reactivity profiles may vary.

3. What are the key safety precautions for handling this solution?

Always handle under nitrogen or argon atmosphere using flame-dried glassware. The solution is highly flammable and reacts violently with water.

4. How does the dimethyl substitution affect reactivity compared to phenylmagnesium bromide?

The electron-donating methyl groups increase nucleophilicity at the ortho/para positions, often resulting in faster reaction rates in electrophilic aromatic substitutions.

5. What’s the recommended procedure for transferring the solution?

Use a dry, inert-gas purged syringe with PTFE plunger or cannula transfer technique under positive nitrogen pressure to prevent moisture contamination.

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