Description
Specifications Table
Product Name – 3,5-Dimethylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 50ML
Form – Liquid (THF solution)
Grade – Research
Application – Grignard reagent for organic synthesis, carbon-carbon bond formation
Product Overview
3,5-Dimethylphenylmagnesium bromide is a specialized Grignard reagent supplied as a 0.5M solution in tetrahydrofuran (THF) under the AcroSeal® packaging system, ensuring maximum stability and protection against moisture contamination. This organomagnesium compound features a dimethyl-substituted phenyl group, offering unique reactivity profiles in nucleophilic addition and substitution reactions. The THF solvent enhances solubility and reactivity while maintaining compatibility with most organic synthesis protocols. The AcroSeal® packaging utilizes an airtight septum cap, allowing for multiple withdrawals without compromising the reagent’s integrity. This product is particularly valued for its consistent performance in carbon-carbon bond formation, aromatic substitution, and complex molecule construction. The 0.5M concentration provides an optimal balance between reagent strength and ease of handling, making it suitable for both small-scale and preparative-scale reactions. All batches undergo rigorous quality control to ensure minimal byproduct formation and high yield potential in synthetic applications.
FAQs
1. What is the typical shelf life of 3,5-Dimethylphenylmagnesium bromide in THF?
The reagent maintains optimal reactivity for 12 months when stored unopened at 2-8°C. Once opened, use within 3 months for best results.
2. Can this be used with water-sensitive substrates?
Yes, the AcroSeal® packaging and anhydrous THF solvent make it suitable for moisture-sensitive reactions when handled under inert atmosphere.
3. What alternatives exist for similar Grignard reactions?
Consider phenylmagnesium bromide for unsubstituted phenyl groups or 2,4-dimethylphenylmagnesium bromide for different regioselectivity patterns.
4. How should the reagent be stored after opening?
Store opened bottles under nitrogen atmosphere at 2-8°C, ensuring the septum cap is properly resealed after each use.
5. What safety precautions are essential when handling this product?
Use in a well-ventilated fume hood with proper PPE, as THF is highly flammable and the reagent is moisture-sensitive and corrosive.
