Description
Specifications Table
Product Name – 4-Dimethylaminoazobenzene-4′-sulfonyl chloride Quantity/Pack Size – 500mg Form – Solid (Powder/Crystals) Grade – 98%+ Application – Organic synthesis, dye intermediates, protein labeling, biochemical research
Product Overview
4-Dimethylaminoazobenzene-4′-sulfonyl chloride (98%+) is a specialized aromatic compound widely utilized in organic synthesis, dye chemistry, and biochemical applications due to its unique sulfonyl chloride functionality and azo linkage. This high-purity reagent exhibits excellent reactivity in nucleophilic substitution reactions, making it ideal for conjugating with amines, alcohols, and thiols to form stable sulfonamide, sulfate, or thiosulfate derivatives. The dimethylamino group enhances solubility in organic solvents while maintaining stability under standard lab conditions. Its vibrant orange-red color serves as a visual indicator in reactions, aiding in monitoring progress without additional reagents. The compound’s sulfonyl chloride moiety is particularly valuable for introducing sulfonic acid groups into molecular structures, enabling modifications in drug discovery, polymer synthesis, and material science. With a purity of 98%+, this product minimizes side reactions and ensures reproducible results in sensitive applications. Store under inert conditions to prevent moisture-induced hydrolysis, and handle with standard precautions for aromatic amines and sulfonyl chlorides. Its versatility extends to cross-linking agents, fluorescent probes, and as a building block for functionalized dyes, offering researchers a reliable tool for innovative chemical transformations.
FAQs
1. What is the solubility of 4-Dimethylaminoazobenzene-4′-sulfonyl chloride in common solvents?
It is soluble in organic solvents like dichloromethane, acetone, and DMF but has limited solubility in water. The dimethylamino group improves solubility in polar aprotic solvents.
2. Can this compound be used for protein labeling or biotinylation?
Yes, the sulfonyl chloride group reacts with primary amines (e.g., lysine residues) to form stable sulfonamide bonds, making it suitable for protein conjugation and labeling.
3. How should this product be stored to maintain stability?
Store in a tightly sealed container under dry, inert conditions (e.g., desiccator or nitrogen atmosphere) at 2–8°C. Avoid exposure to moisture or humidity to prevent hydrolysis.
4. What safety precautions are recommended when handling this chemical?
Wear nitrile gloves, safety goggles, and a lab coat. Work in a fume hood due to potential irritation from dust or vapors. Avoid inhalation and skin contact, as it may cause sensitization.
5. Are there alternatives for applications requiring lower reactivity?
For milder conditions, consider sulfonyl fluorides or activated esters (e.g., NHS-esters), though they may require longer reaction times or catalysts for comparable yields.
