Specifications Table

Product Name – 4-Fluoro-3-methylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 50ML
Form – Solution
Grade – Reagent
Application – Organic synthesis, Grignard reactions

Product Overview

4-Fluoro-3-methylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal® is a high-purity Grignard reagent designed for precision in organic synthesis. This reagent-grade solution is stabilized in tetrahydrofuran (THF), ensuring optimal reactivity and shelf life. The AcroSeal® packaging guarantees minimal exposure to moisture and air, preserving the reagent’s integrity for consistent performance in laboratory applications. The 0.5M concentration provides a balanced reactivity profile, making it suitable for a wide range of synthetic transformations, including carbon-carbon bond formation and nucleophilic additions. The presence of the fluoro and methyl substituents on the phenyl ring enhances selectivity in specific reactions, offering researchers greater control over product outcomes. This reagent is ideal for demanding synthetic routes where purity and reproducibility are critical. Store under inert conditions to maintain stability and extend usability.

FAQs

1. What is the shelf life of 4-fluoro-3-methylphenylmagnesium bromide in THF?

The shelf life is typically 12 months from the date of manufacture when stored unopened under inert conditions at recommended temperatures.

2. Can this reagent be used directly in Grignard reactions without further purification?

Yes, the AcroSeal® packaging ensures high purity, allowing direct use in reactions without additional purification steps.

3. What precautions should be taken while handling this solution?

Handle under an inert atmosphere (nitrogen or argon) to prevent moisture contamination, which can decompose the Grignard reagent.

4. Is this solution compatible with all common organic solvents?

It is stable in THF but may react violently with protic solvents like water or alcohols. Always check compatibility before mixing.

5. What is the recommended storage temperature for this reagent?

Store at 2-8°C in a tightly sealed container under inert gas to maintain stability and prevent degradation.