Specifications Table

Product Name – 4-Fluorophenylmagnesium bromide, 2M solution in diethyl ether, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Solution
Grade – Reagent
Application – Grignard reactions, fluorinated aromatic synthesis

Product Overview

This 2M solution of 4-fluorophenylmagnesium bromide in diethyl ether is a highly reactive Grignard reagent designed for demanding organic synthesis applications. The fluorinated phenyl group enables selective halogen-metal exchange reactions while maintaining stability in anhydrous conditions. Packaged under nitrogen in AcroSeal® bottles to prevent moisture contamination, this reagent offers consistent 2M concentration for reproducible results in nucleophilic addition and coupling reactions. The ether solvent system provides optimal solubility for the organomagnesium species while allowing precise control over reaction kinetics. Each batch undergoes rigorous quality testing to ensure minimal byproduct formation and maximum reactivity. The solution’s air-sensitive nature requires proper handling under inert atmosphere for optimal performance. Ideal for laboratories requiring high-purity fluorinated aromatic building blocks in multi-step synthetic pathways.

FAQs

1. What is the typical shelf life of this Grignard reagent solution?

When stored unopened at 2-8°C under nitrogen, the solution maintains its 2M concentration for 12 months from the date of manufacture. Always verify the bottle’s expiration date before use.

2. Can this reagent be used directly in THF solvent systems?

The diethyl ether solution can be transferred to THF, but note that solvent exchange may slightly alter the effective concentration due to differing solvent densities.

3. What safety precautions are essential when handling this product?

Always work in a properly ventilated fume hood, wear moisture-resistant gloves, and use flame-proof equipment due to the ether’s flammability and the reagent’s air/moisture sensitivity.

4. How should I dispose of unused solution?

Slowly quench with isopropanol or saturated ammonium chloride solution in a well-ventilated area before disposal according to local hazardous waste regulations.

5. What’s the difference between AcroSeal® and standard packaging?

AcroSeal® bottles feature a specialized septum system that maintains inert atmosphere during multiple punctures, reducing oxygen/moisture contamination compared to traditional screw-cap bottles.