Specifications Table

Product Name – 4-Isopropylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 50ML
Form – Solution
Grade – Reagent
Application – Grignard reagent for organic synthesis

Product Overview

4-Isopropylphenylmagnesium bromide, supplied as a 0.5M solution in anhydrous THF, is a highly reactive Grignard reagent designed for precision organic synthesis. The AcroSeal® packaging ensures minimal exposure to moisture and oxygen, preserving the reagent’s integrity for consistent performance in nucleophilic addition and coupling reactions. This solution is stabilized under inert conditions, making it suitable for demanding laboratory applications where purity and reactivity are critical. The reagent’s structure, featuring an isopropyl-substituted phenyl ring, enhances selectivity in aromatic substitutions, while the THF solvent provides optimal solubility for homogeneous reactions. As a reagent-grade solution, it meets stringent quality standards for reproducibility in research and development workflows. The sealed packaging format minimizes handling risks and extends shelf life, reducing waste in high-frequency laboratory settings.

FAQs

1. What is the typical shelf life of this Grignard reagent in AcroSeal® packaging?

The reagent remains stable for 12 months when stored unopened at 2-8°C under inert conditions, though frequent exposure to air may reduce potency.

2. Can this solution be used directly in reactions without further purification?

Yes, the 0.5M solution is provided in reagent-grade purity and requires no additional purification for most standard Grignard applications.

3. Is this compatible with glassware treated with standard drying agents?

Absolutely, but ensure all glassware is thoroughly dried and flushed with inert gas to prevent premature decomposition of the reagent.

4. What alternatives exist for similar isopropyl-substituted phenyl Grignard reagents?

Alternatives include 4-isopropylphenyllithium or the corresponding chloride derivative, though reactivity profiles and solvent compatibility may vary.

5. How should unused solution be disposed of after opening?

Neutralize with isopropanol or a dilute acid solution in a well-ventilated fume hood, then follow local hazardous waste disposal protocols.